Using omics approaches to understand pulmonary diseases

M Kan, M Shumyatcher, BE Himes - Respiratory research, 2017 - Springer
Omics approaches are high-throughput unbiased technologies that provide snapshots of
various aspects of biological systems and include: 1) genomics, the measure of DNA …

[HTML][HTML] Biophotonics technologies for the detection of VOCs in healthcare applications: Are we there yet?

S Zhang, K Vinod Ram, RZT Chua, JCY Foo… - Applied Physics …, 2023 - pubs.aip.org
The detection of volatile organic compounds (VOCs) has emerged as one of the most
promising diagnostic approaches in the field of medicine. For example, human breath …

UV laser-based photoacoustic breath analysis for the diagnosis of respiratory diseases: Detection of Asthma

VR Nidheesh, AK Mohapatra, R Nayak… - Sensors and Actuators B …, 2022 - Elsevier
Photoacoustic spectroscopy (PAS) can detect volatile organic compounds (VOCs) present in
exhaled breath with very high sensitivity. A PAS setup using laser excitation at 266 nm and …

A pilot study of the effect of phospholipid curcumin on serum metabolomic profile in patients with non-alcoholic fatty liver disease: a randomized, double-blind, placebo …

S Chashmniam, SR Mirhafez, M Dehabeh… - European journal of …, 2019 - nature.com
Abstract Background/Objectives Curcumin, a natural polyphenol compound in the spice
turmeric, has been found to have potent anti-oxidative and anti-inflammatory activity …

High-fiber diets attenuate emphysema development via modulation of gut microbiota and metabolism

YO Jang, OH Kim, SJ Kim, SH Lee, S Yun, SE Lim… - Scientific reports, 2021 - nature.com
Dietary fiber functions as a prebiotic to determine the gut microbe composition. The gut
microbiota influences the metabolic functions and immune responses in human health. The …

Strategies and challenges in method development and validation for the absolute quantification of endogenous biomarker metabolites using liquid chromatography …

MM Khamis, DJ Adamko… - Mass spectrometry …, 2021 - Wiley Online Library
Metabolomics is a dynamically evolving field, with a major application in identifying
biomarkers for drug development and personalized medicine. Numerous metabolomic …

Associations of nasopharyngeal metabolome and microbiome with severity among infants with bronchiolitis. A multiomic analysis

CJ Stewart, JM Mansbach, MC Wong… - American journal of …, 2017 - atsjournals.org
Rationale: Bronchiolitis is the most common lower respiratory infection in infants; however, it
remains unclear which infants with bronchiolitis will develop severe illness. In addition …

A review of analytical techniques and their application in disease diagnosis in breathomics and salivaomics research

DJ Beale, OAH Jones, AV Karpe, S Dayalan… - International journal of …, 2016 - mdpi.com
The application of metabolomics to biological samples has been a key focus in systems
biology research, which is aimed at the development of rapid diagnostic methods and the …

A high-performing plasma metabolite panel for early-stage lung cancer detection

L Zhang, J Zheng, R Ahmed, G Huang, J Reid… - Cancers, 2020 - mdpi.com
The objective of this research is to use metabolomic techniques to discover and validate
plasma metabolite biomarkers for the diagnosis of early-stage non-small cell lung cancer …

Breathomics: review of sample collection and analysis, data modeling and clinical applications

M Khoubnasabjafari, MRA Mogaddam… - Critical Reviews in …, 2022 - Taylor & Francis
Metabolomics research is rapidly gaining momentum in disease diagnosis, on top of other
Omics technologies. Breathomics, as a branch of metabolomics is developing in various …