COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Comparative systematic review and meta-analysis of reactogenicity, immunogenicity and efficacy of vaccines against SARS-CoV-2

I McDonald, SM Murray, CJ Reynolds, DM Altmann… - npj Vaccines, 2021 - nature.com
As SARS-CoV-2 vaccines are deployed worldwide, a comparative evaluation is important to
underpin decision-making. We here report a systematic literature review and meta-analysis …

Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19

Y Yang, C Shen, J Li, J Yuan, J Wei, F Huang… - Journal of Allergy and …, 2020 - Elsevier
Background The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome coronavirus 2 was first reported in Wuhan, December 2019, and …

DNA vaccines against COVID-19: Perspectives and challenges

MM Silveira, GMSG Moreira, M Mendonça - Life sciences, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus known
as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated …

Pulmonary fibrosis in COVID‐19 survivors: Predictive factors and risk reduction strategies

AS Ojo, SA Balogun, OT Williams… - Pulmonary medicine, 2020 - Wiley Online Library
Although pulmonary fibrosis can occur in the absence of a clear‐cut inciting agent, and
without a clinically clear initial acute inflammatory phase, it is more commonly associated …

COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies

K Rawat, P Kumari, L Saha - European journal of pharmacology, 2021 - Elsevier
Coronavirus Disease 2019 named as COVID-19 imposing a huge burden on public health
as well as global economies, is caused by a new strain of betacoronavirus named as SARS …

Coronavirus infections and immune responses

G Li, Y Fan, Y Lai, T Han, Z Li, P Zhou… - Journal of medical …, 2020 - Wiley Online Library
Coronaviruses (CoVs) are by far the largest group of known positive‐sense RNA viruses
having an extensive range of natural hosts. In the past few decades, newly evolved …

Drug targets for corona virus: A systematic review

M Prajapat, P Sarma, N Shekhar, P Avti… - Indian journal of …, 2020 - journals.lww.com
Abstract The 2019-novel coronavirus (nCoV) is a major source of disaster in the 21 th
century. However, the lack of specific drugs to prevent/treat an attack is a major need at this …

Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1 …

DY Logunov, IV Dolzhikova, OV Zubkova… - The Lancet, 2020 - thelancet.com
Background We developed a heterologous COVID-19 vaccine consisting of two
components, a recombinant adenovirus type 26 (rAd26) vector and a recombinant …

Emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2: biology and therapeutic options

S Khan, R Siddique, MA Shereen, A Ali… - Journal of clinical …, 2020 - Am Soc Microbiol
The new decade of the 21st century (2020) started with the emergence of a novel
coronavirus known as SARS-CoV-2 that caused an epidemic of coronavirus disease …