Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

European Society of Cardiology: cardiovascular disease statistics 2021

A Timmis, P Vardas, N Townsend… - European heart …, 2022 - academic.oup.com
Aims This report from the European Society of Cardiology (ESC) Atlas Project updates and
expands upon the widely cited 2019 report in presenting cardiovascular disease (CVD) …

Epidemiology of cardiovascular disease in Europe

N Townsend, D Kazakiewicz, F Lucy Wright… - Nature Reviews …, 2022 - nature.com
This Review presents data describing the health burden of cardiovascular disease (CVD)
within and across the WHO European Region. CVD remains the most common cause of …

[HTML][HTML] Role and mechanism of gut microbiota in human disease

Y Chen, J Zhou, L Wang - Frontiers in cellular and infection …, 2021 - frontiersin.org
The human gut microbiome is a huge microbial community that plays an irreplaceable role
in human life. With the further development of research, the influence of intestinal flora on …

The global epidemiology of hypertension

KT Mills, A Stefanescu, J He - Nature Reviews Nephrology, 2020 - nature.com
Hypertension is the leading cause of cardiovascular disease and premature death
worldwide. Owing to the widespread use of antihypertensive medications, global mean …

European Society of Cardiology: cardiovascular disease statistics 2019

A Timmis, N Townsend, CP Gale, A Torbica… - European heart …, 2020 - academic.oup.com
Aims The 2019 report from the European Society of Cardiology (ESC) Atlas provides a
contemporary analysis of cardiovascular disease (CVD) statistics across 56 member …

Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta …

M Huhn, A Nikolakopoulou, J Schneider-Thoma… - The Lancet, 2019 - thelancet.com
Background Schizophrenia is one of the most common, burdensome, and costly psychiatric
disorders in adults worldwide. Antipsychotic drugs are its treatment of choice, but there is …

Environmental endocrine-disrupting chemical exposure: role in non-communicable diseases

M Kumar, DK Sarma, S Shubham, M Kumawat… - Frontiers in public …, 2020 - frontiersin.org
The exponential growth of pollutant discharges into the environment due to increasing
industrial and agricultural activities is a rising threat for human health and a biggest concern …

Trends in worldwide asthma prevalence

MI Asher, L García-Marcos, NE Pearce… - European …, 2020 - Eur Respiratory Soc
This review of trends in worldwide asthma prevalence starts with defining how asthma
prevalence is measured in populations and how it is analysed. Four population studies of …