The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

OBJECTIVES: Arthritis, surgery, and traumatic injury of the knee joint are associated with
long-lasting inability to fully activate the quadriceps muscle, a process known as arthrogenic …

Objective Pain sensitization is associated with pain severity in knee osteoarthritis (OA), but
its cause in humans is not well understood. We examined whether inflammation, assessed …

One of the cardinal features of inflammatory states is that normally innocuous stimuli
produce pain. Since the publication of the Melzack±Wall gate control theory in 1965, 45 it …

Background The anterior cruciate ligament (ACL) plays a major role in knee proprioception
and is thus responsible for maintaining knee joint stability and functionality. The available …

1. Introduction......................................... II. Anatomy and physiology................................ A. The
peripheral apparatus............................. Fiber composition of muscle nerves …

The third edition of this monograph continues to have the goal of providing an overview of
current thought about the spinal cord mechanisms that are responsible for sensory …

Review Article Afferent and spinal mechanisms of joint pain Page 1 Pain, 55 (1993) 5-54 0
1993 Elsevier Science Publishers BV All rights reserved 0304-3959/93/$06.00 5 PAIN …

One hundred ninety-four cutaneous C-fibers were recorded from the human peroneal nerve;
118 units were found by mechanical stimuli and 76 units were detected by electrical …

Defines proprioception and its functions in human skin, muscles, and joint tissues.
Proprioception as a compound sense; Position sense largely mediated by activity in muscle …