Cholangiocarcinoma 2020: the next horizon in mechanisms and management

JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

Surgery for cholangiocarcinoma

U Cillo, C Fondevila, M Donadon, E Gringeri… - Liver …, 2019 - Wiley Online Library
Surgical resection is the only potentially curative treatment for patients with
cholangiocarcinoma. For both perihilar cholangiocarcinoma (pCCA) and intrahepatic …

Predicting futility of upfront surgery in perihilar cholangiocarcinoma: Machine learning analytics model to optimize treatment allocation

F Ratti, R Marino, PB Olthof, J Pratschke, JI Erdmann… - Hepatology, 2024 - journals.lww.com
Background: While resection remains the only curative option for perihilar
cholangiocarcinoma, it is well known that such surgery is associated with a high risk of …

Machine‐learning radiomics to predict early recurrence in perihilar cholangiocarcinoma after curative resection

H Qin, X Hu, J Zhang, H Dai, Y He, Z Zhao… - Liver …, 2021 - Wiley Online Library
Background and aims Up to 40%‐65% of patients with perihilar cholangiocarcinoma (PHC)
rapidly progress to early recurrence (ER) even after curative resection. Quantification of ER …

Racial Segregation among patients with cholangiocarcinoma—impact on diagnosis, treatment, and outcomes

MM Munir, S Woldesenbet, Y Endo, HA Lima… - Annals of Surgical …, 2023 - Springer
Background Racial segregation, an effect of historical marginalization, may impact cancer
care and outcomes. We sought to examine the impact of racial segregation on the diagnosis …

Precision oncology targets in biliary tract cancer

N Farha, D Dima, F Ullah, S Kamath - Cancers, 2023 - mdpi.com
Simple Summary Biliary tract cancer is rare in the US but remains a highly lethal cancer.
While the standard of care in the first-line, metastatic setting is well-established, no second …

Disparities in NCCN guideline compliant care for resectable cholangiocarcinoma at minority-serving versus non-minority-serving hospitals

DI Tsilimigras, D Dalmacy, JM Hyer, A Diaz… - Annals of surgical …, 2021 - Springer
Background Racial/ethnic disparities in cancer outcomes may relate to variations in receipt
of National Comprehensive Cancer Network (NCCN) guideline compliant care. Patients and …

Development and validation of noninvasive MRI‐based signature for preoperative prediction of early recurrence in Perihilar cholangiocarcinoma

J Zhao, W Zhang, YY Zhu, HY Zheng… - Journal of Magnetic …, 2022 - Wiley Online Library
Background Cholangiocarcinoma is a type of hepatobiliary tumor. For perihilar
cholangiocarcinoma (pCCA), patients who experience early recurrence (ER) have a poor …

[HTML][HTML] Feasibility of magnetic resonance imaging-based radiomics features for preoperative prediction of extrahepatic cholangiocarcinoma stage

X Huang, J Shu, Y Yan, X Chen, C Yang… - European Journal of …, 2021 - Elsevier
Aim The aim of this study is to develop and test radiomics models based on magnetic
resonance imaging (MRI) to preoperatively and respectively predict the T stage, perineural …

[HTML][HTML] Resection for Klatskin tumors: technical complexities and results

I Capobianco, J Rolinger, S Nadalin - Translational …, 2018 - ncbi.nlm.nih.gov
Klatskin's tumors, actually-redefined as perihilar cholangiocarcinoma (phCCA) do represent
50–70% of all CCAs and develop in a context of chronic inflammation and cholestasis of bile …