MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

N Amodio, L Raimondi, G Juli, MA Stamato… - Journal of hematology & …, 2018 - Springer
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …

MALAT1 Long Non-Coding RNA: Functional Implications

G Arun, D Aggarwal, DL Spector - Non-coding RNA, 2020 - mdpi.com
The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …

MALAT1: a potential biomarker in cancer

ZX Li, QN Zhu, HB Zhang, Y Hu, G Wang… - Cancer management …, 2018 - Taylor & Francis
Purpose The research of long non-coding RNAs (lncRNAs) has become a new passion with
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …

Long noncoding RNA Malat1 regulates cerebrovascular pathologies in ischemic stroke

X Zhang, X Tang, K Liu, MH Hamblin… - Journal of …, 2017 - Soc Neuroscience
The study was designed to determine the role of long noncoding RNA (lncRNA), metastasis-
associated lung adenocarcinoma transcript 1 (Malat1), in ischemic stroke outcome. Primary …

TUG 1: a pivotal oncogenic long non‐coding RNA of human cancers

Z Li, J Shen, MTV Chan, WKK Wu - Cell proliferation, 2016 - Wiley Online Library
Long non‐coding RNA s (lnc RNA s) are a group greater than 200 nucleotides in length. An
increasing number of studies has shown that lnc RNA s play important roles in diverse …

[HTML][HTML] Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing

Y Liu, H Tian, Y Hu, Y Cao, H Song, S Lan… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The biomechanical environment plays a dominant role in fracture healing, and Piezo1 is
regarded as a major mechanosensor in bone homeostasis. However, the role of Piezo1 in …

LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis

Y Tang, Y He, P Zhang, J Wang, C Fan, L Yang… - Molecular cancer, 2018 - Springer
Some of the key steps in cancer metastasis are the migration and invasion of tumor cells;
these processes require rearrangement of the cytoskeleton. Actin filaments, microtubules …

Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma

Z Yang, X Li, Y Yang, Z He, X Qu, Y Zhang - Cell death & disease, 2016 - nature.com
Long noncoding RNAs (lncRNAs) are a class of non-protein-coding molecules longer than
200 nucleotides that are involved in the development and progression of many types of …

[HTML][HTML] Long non-coding RNA MALAT1 for promoting metastasis and proliferation by acting as a ceRNA of miR-144-3p in osteosarcoma cells

Y Wang, Y Zhang, T Yang, W Zhao, N Wang, P Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are involved in various biological processes and
diseases including osteosarcoma. Long non-coding RNA metastasis-associated lung …

MALAT1 promotes osteosarcoma development by regulation of HMGB1 via miR-142–3p and miR-129–5p

K Liu, J Huang, J Ni, D Song, M Ding, J Wang… - Cell cycle, 2017 - Taylor & Francis
Recently, emerging evidence has demonstrated that metastasis-associated lung
adenocarcinoma transcript 1 (MALAT1), a long non-coding RNAs (lncRNAs), contributes to …