Tooth enamel secreted by ameloblasts (AMs) is the hardest material in the human body,
acting as a shield to protect the teeth. However, the enamel is gradually damaged or …

Epigenetic regulation, mainly involving DNA methylation, histone modification, and
noncoding RNAs, affects gene expression without modifying the primary DNA sequence and …

Dental pulp stem cells (DPSC) usually remain quiescent in the dental pulp tissue; however,
once the dental pulp tissue is injured, DPSCs potently proliferate and migrate into the injury …

Background Adipose-derived mesenchymal stem cells (ADMSCs) have attracted
widespread interest as cell-based tissue repair systems. To obtain adequate quantities of …

Background Dental pulp stem cells (DPSCs) are a promising cell source in endodontic
regeneration and tissue engineering with limited self-renewal and pluripotency capacity. N 6 …

Highlights•Drosophila female germline stem cells (GSCs) can be used as a highly sensitive
injury model of aging.•The earliest observable phenotype of aging in GSCs is permanent …

Hyaluronic acid (HA), an extracellular biopolymer found throughout the human body, holds
promise as a biocompatible and biodegradable scaffold material. High molecular weight …

To investigate the characteristics and molecular events of dental pulp stem cells (DPSCs) for
tissue regeneration with aging, we isolated and analyzed the stem cells from human …

Cellular senescence affects the efficacy of mesenchymal stem cells (MSCs)-mediated tissue
regeneration. Insulin-like growth factor binding proteins-7 (IGFBP7), as a member of the IGF …

Cellular senescence severely limits the research and the application of dental pulp stem
cells (DPSCs). A previous study conducted by our research group revealed a close …