Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

The triplet state of organo-transition metal compounds. Triplet harvesting and singlet harvesting for efficient OLEDs

H Yersin, AF Rausch, R Czerwieniec, T Hofbeck… - Coordination Chemistry …, 2011 - Elsevier
Based on a very comprehensive set of experimental data and on theoretical models, an
understanding of the triplet state properties of organo-transition metal compounds is worked …

Phosphorescent heavy-metal complexes for bioimaging

Q Zhao, C Huang, F Li - Chemical Society Reviews, 2011 - pubs.rsc.org
The application of phosphorescent heavy-metal complexes with d6, d8 and d10 electron
configurations for bioimaging is a new and promising research field and has been attracting …

Lighting the way to see inside the live cell with luminescent transition metal complexes

E Baggaley, JA Weinstein, JAG Williams - Coordination Chemistry Reviews, 2012 - Elsevier
The application of luminescent metal complexes to cell imaging is a rapidly emerging area.
This review discusses the background to the field, the advantages that such complexes may …

Application of d6 transition metal complexes in fluorescence cell imaging

V Fernández-Moreira, FL Thorp-Greenwood… - Chemical …, 2010 - pubs.rsc.org
Luminescent d6 transition metal complexes have often been proposed as useful
fluorophores for cell imaging due to their attractive photophysical attributes, but until very …

Underestimated potential of organometallic rhenium complexes as anticancer agents

A Leonidova, G Gasser - ACS chemical biology, 2014 - ACS Publications
In the recent years, organometallic compounds have become recognized as promising anti-
cancer drug candidates. While radioactive 186/188Re compounds are already used in …

Design of luminescent iridium (III) and rhenium (I) polypyridine complexes as in vitro and in vivo ion, molecular and biological probes

KKW Lo, MW Louie, KY Zhang - Coordination Chemistry Reviews, 2010 - Elsevier
Many luminescent transition metal polypyridine complexes display intense and long-lived
triplet charge-transfer and intraligand transition emission with a large Stokes' shift. These …

Design of targeting ligands in medicinal inorganic chemistry

T Storr, KH Thompson, C Orvig - Chemical Society Reviews, 2006 - pubs.rsc.org
This tutorial review will highlight recent advances in medicinal inorganic chemistry
pertaining to the use of multifunctional ligands for enhanced effect. Ligands that adequately …

'Two is better than one'—probes for dual-modality molecular imaging

LE Jennings, NJ Long - Chemical communications, 2009 - pubs.rsc.org
Molecular or personalised medicine is the future of patient management and healthcare,
and molecular imaging plays a key role towards this goal. However, amongst molecular …

Synthesis and evaluation of technetium-99m-and rhenium-labeled inhibitors of the prostate-specific membrane antigen (PSMA)

SR Banerjee, CA Foss, M Castanares… - Journal of medicinal …, 2008 - ACS Publications
The prostate-specific membrane antigen (PSMA) is increasingly recognized as a viable
target for imaging and therapy of cancer. We prepared seven 99mTc/Re-labeled compounds …