Overview of next‐generation sequencing technologies

BE Slatko, AF Gardner… - Current protocols in …, 2018 - Wiley Online Library
High throughput DNA sequencing methodology (next generation sequencing; NGS) has
rapidly evolved over the past 15 years and new methods are continually being …

High-throughput glycomic methods

I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

F Cuskin, EC Lowe, MJ Temple, Y Zhu, EA Cameron… - Nature, 2015 - nature.com
Yeasts, which have been a component of the human diet for at least 7,000 years, possess
an elaborate cell wall α-mannan. The influence of yeast mannan on the ecology of the …

Synthesis, molecular features and biological activities of modified plant polysaccharides

S Mukherjee, S Jana, S Khawas, J Kicuntod… - Carbohydrate …, 2022 - Elsevier
Plant polysaccharides represent a natural source material characterized by high ubiquity,
abundance and biological activities that can be utilised as organic matter in numerous …

A systematic approach to protein glycosylation analysis: a path through the maze

K Marino, J Bones, JJ Kattla, PM Rudd - Nature chemical biology, 2010 - nature.com
Protein glycosylation is an important post-translational modification. It is a feature that
enhances the functional diversity of proteins and influences their biological activity. A wide …

Glycan labeling strategies and their use in identification and quantification

LR Ruhaak, G Zauner, C Huhn, C Bruggink… - Analytical and …, 2010 - Springer
Most methods for the analysis of oligosaccharides from biological sources require a glycan
derivatization step: glycans may be derivatized to introduce a chromophore or fluorophore …

Synthesis and medical applications of oligosaccharides

PH Seeberger, DB Werz - Nature, 2007 - nature.com
Our understanding of the different glycoconjugates present on cells, proteins and entire
organisms is lagging far behind advances in genomics and proteomics. Carbohydrate …

Cotton HILIC SPE microtips for microscale purification and enrichment of glycans and glycopeptides

MHJ Selman, M Hemayatkar, AM Deelder… - Analytical …, 2011 - ACS Publications
Solid-phase extraction microtips are important devices in modern bioanalytics, as they allow
miniaturized sample preparation for mass spectrometric analysis. Here we introduce the use …

Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis

I Cambré, D Gaublomme, A Burssens… - Nature …, 2018 - nature.com
Many pro-inflammatory pathways leading to arthritis have global effects on the immune
system rather than only acting locally in joints. The reason behind the regional and patchy …

Focus on antivirally active sulfated polysaccharides: from structure–activity analysis to clinical evaluation

T Ghosh, K Chattopadhyay, M Marschall… - …, 2009 - academic.oup.com
In recent years, many compounds having potent antiviral activity in cell culture have been
detected and some of these compounds are currently undergoing either preclinical or …