Simple Summary Prostate cancer is the most common malignancy in men, with a high
mortality rate when disease progresses to metastasis and therapeutic resistance. Evidence …

While meant for wound healing and immunity in response to injury and infection,
inflammatory signaling is usurped by cancerous tumors to promote disease progression …

Abstract Prostate Cancer (PCa) is the second leading cause of cancer-related death in men.
Adenocarcinoma of the prostate is primarily composed of Androgen Receptor-positive (AR+) …

Introduction Inflammation plays a significant role in various cancers, including lung cancer,
where the inflammatory cytokine IL-1β is often elevated in the tumor microenvironment …

Prostate cancer is one of the main global health threats for men which is in close association
with chronic inflammation. Neuropeptide substance P (SP), acting through neurokinin …

Transcriptional regulation plays a crucial role in determining cell fate and disease, yet
inferring the key regulators from gene expression data remains a significant challenge …

Simple Summary Prostate cancer is the most frequently diagnosed non-cutaneous tumor in
men in the Western world. Therapy for non-organ confined prostate cancer includes anti …

Reproductive cancers are malignancies that develop in the reproductive organs. One of the
leading cancers affecting the male reproductive system on a global scale is prostate cancer …

Chronic inflammation promotes prostate cancer (PCa) initiation and progression. We
previously reported that acute intereluekin-1 (IL-1) exposure represses androgen receptor …

Chronic prostate inflammation in patients with benign prostate hyperplasia (BPH) correlates
with the severity of symptoms. How inflammation contributes to prostate enlargement and/or …