Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

In recent years, nanoparticle-based formulations have emerged as smart platforms for
diagnosing and treating a wide range of diseases. However, upon systematic administration …

The complex pathological mechanism of Alzheimer's disease (AD) limits the efficacy of
simple drug therapy, and drugs are difficult to penetrate the blood‐brain barrier (BBB) …

Abstract Bromodomain-containing protein 4 (BRD4) is the most well-studied BET protein that
is important for the innate immune response. We recently revealed that targeting BRD4 …

Macrophage uptake of nanoparticles is highly dependent on the physicochemical
characteristics of those nanoparticles. Here, we have created a collection of lipid-polymer …

Apoptotic bodies (ABs) are extracellular vesicles released during apoptosis and possess
diverse biological activities. Initially, ABs were regarded as garbage bags with the main …

Modulation of the immune system has gained significant attention in regenerative medicine.
Although most tissues possess intrinsic self-repair capabilities, large-sized defects and …

Simple Summary This review assesses the integration of nanotechnology and
immunotherapy, with a specific focus on the utilization of nanomaterials to modulate the …

Messenger RNA (mRNA) therapeutics have garnered considerable attention due to their
remarkable efficacy in the treatment of various diseases. The COVID‐19 mRNA vaccine and …

Graft tolerance is a pathophysiological condition heavily reliant on the dynamic interaction of
the innate and adaptive immune systems. Genetic polymorphism determines immune …