Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: a review of agents and causative mechanisms

U Nair, H Bartsch, J Nair - Mutagenesis, 2004 - academic.oup.com
Abstract In south‐east Asia, Taiwan and Papua New Guinea, smoking, alcohol consumption
and chewing of betel quid with or without tobacco or areca nut with or without tobacco are …

Tobacco‐specific N‐nitrosamines and ARECA‐derived N‐nitrosamines: Chemistry, biochemistry, carcinogenicity, and relevance to humans

D Hoffmann, KD Brunnemann… - Journal of Toxicology …, 1994 - Taylor & Francis
Nicotine and the minor tobacco alkaloids give rise to tobacco‐specific N‐nitrosamines
(TSNA) during tobacco processing and during smoking. Chemical‐analytical studies led to …

N-nitroso compounds and man: sources of exposure, endogenous formation and occurrence in body fluids

AR Tricker - European journal of cancer prevention, 1997 - journals.lww.com
Based on recent analytical data, total human exoenous exposure to N-nitrosamines is
estimated to be 1.10 [mu] mol/day: the major exposure sources are the diet (0.79 [mu] …

IARC monographs on the evaluation of carcinogenic risks to humans

AJ Zuckerman - Journal of Clinical Pathology, 1995 - pmc.ncbi.nlm.nih.gov
Viral hepatitis in all its forms is a major public health problem throughout the world, affecting
several hundreds of millions of people. Viral hepatitis is a cause of considerable morbidity …

[图书][B] Smokeless tobacco and some tobacco-specific N-nitrosamines

IARC Working Group on the Evaluation of … - 2007 - books.google.com
This eighty-ninth volume of the IARC Monographs is the third and last of a series on tobacco-
related agents. Volume 83 reported on the carcinogenicity of tobacco smoke and involuntary …

Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: tobacco exposure as a risk modulator

D Anantharaman, PM Chaubal, S Kannan… - …, 2007 - academic.oup.com
Oral cancer is the leading cancer type among Southeast Asian men and is causally
associated with the use of tobacco. Genetic polymorphisms in xenobiotic-metabolizing …

Chemistry and toxicology of smokeless tobacco

RA Bhisey - Indian Journal of Cancer, 2012 - journals.lww.com
In most parts of the world, tobacco is used for smoking, whereas, in India, tobacco is used for
smoking as well as in diverse smokeless forms. Absorption of toxic and carcinogenic …

How each component of betel quid is involved in oral carcinogenesis: mutual interactions and synergistic effects with other carcinogens—a review article

S Islam, M Muthumala, H Matsuoka, O Uehara… - Current oncology …, 2019 - Springer
Abstract Purpose of Review The roles of the components of betel quid in oral carcinogenesis
remain unclear. The purpose of the present review is to highlight the effect of each …

Role of areca nut consumption in the cause of oral cancers. A cytogenetic assessment

BJ Dave, AH Trivedi, SG Adhvatyu - Cancer, 1992 - Wiley Online Library
Background. Cytogenetic studies, framed to assess the possible genomic damage caused
by areca nut consumption (without tobacco and not as a component of betel quid), were …

Cytogenetic damage in exfoliated oral mucosal cells and circulating lymphocytes of patients suffering from precancerous oral lesions

SS Desai, SD Ghaisas, SD Jakhi, SV Bhide - Cancer letters, 1996 - Elsevier
One hundred patients suffering from oral submucous fibrosis (OSF), oral leukoplakia (OL)
and oral lichen planus (OLP) were studied for the cytogenetic damage in oral mucosal cells …