Biomarkers for hepatocellular carcinoma: from origin to clinical diagnosis

MA Omar, MM Omran, K Farid, AA Tabll, YE Shahein… - Biomedicines, 2023 - mdpi.com
The incidence of hepatocellular carcinoma (HCC) and HCC-related deaths has increased
over the last few decades. There are several risk factors of HCC such as viral hepatitis (B …

Overview of MicroRNAs as diagnostic and prognostic biomarkers for high-incidence cancers in 2021

C Zhang, C Sun, Y Zhao, Q Wang, J Guo, B Ye… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs (ncRNAs) about 22 nucleotides in size,
which play an important role in gene regulation and are involved in almost all major cellular …

Long-term effect of anesthesia choice on patients with hepatocellular carcinoma undergoing open liver resection

R Zhao, X Xu, L Sun, G Zhang - Frontiers in Oncology, 2023 - frontiersin.org
Clinical and experimental evidence suggested that anesthesia choice can influence cancer
progression and patients' outcomes by modulating tumor microenvironment and tumorigenic …

Implication of miR-122, miR-483, and miR-335 expression levels as potential signatures in HCV-related hepatocellular carcinoma (HCC) in Egyptian patients

AY Elfert, A Salem, AM Abdelhamid… - Frontiers in Molecular …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related
deaths worldwide with chronic hepatitis C virus (HCV) infection as a major risk factor of …

MicroRNA-29a and MicroRNA-124 as novel biomarkers for hepatocellular Carcinoma

S Shehab-Eldeen, MF Metwaly, SM Saber… - Digestive and Liver …, 2023 - Elsevier
Abstract Background Numerous microRNAs (miRNAs) have been observed to be
abnormally expressed in cancer. Therefore, miRNA signatures could be potential …

Current updates on the molecular and genetic signals as diagnostic and therapeutic targets for hepatitis B virus-associated hepatic malignancy

A Adugna, Y Muche, A Melkamu, M Jemal, H Belew… - Heliyon, 2024 - cell.com
Liver cancer caused by the hepatitis B virus (HBV) is the third most common cancer-related
cause of death worldwide. Early detection of HBV-caused hepatic tumors increases the …

Blood-based biomarkers in AFP normal/stable hepatocellular carcinoma: Diagnostic and prognostic relevance of miR-10b for patients on liver transplant list

F Aksoy, SA Aksoy, HZ Dundar, B Tunca… - Transplantation …, 2022 - Elsevier
Background As a diagnostic criteria of hepatocellular carcinoma (HCC), the exact threshold
of alpha-fetoprotein (AFP) is controversial. In additional, not all HCC tumors are AFP positive …

Expression of PVT-1 and miR-29a/29b as reliable biomarkers for liver cirrhosis and their correlation with the inflammatory biomarkers profile.

SE Khalaf, SN Abdelfattah… - Human & …, 2024 - journals.sagepub.com
Background & Aims The liver is a vital organ responsible for numerous metabolic processes,
which can be significantly impacted by long non-coding RNAs (lncRNAs) and microRNAs …

NAFLD mark: an accurate model based on microRNA-34 for diagnosis of non-alcoholic fatty liver disease patients

AA Mohamed, A El-Demery, E Al-Hussain… - Journal of Genetic …, 2021 - Springer
Background It remains essential for non-alcoholic fatty liver (NAFLD) patients, to develop a
sensitive and specific diagnostic model. Data regarding the use of micro (mi) RNA-34 for …

Development and validation of a novel circulating miRNA-based diagnostic score for early detection of hepatocellular carcinoma

B Yu, S Zhou, H Liang, Q Ye, Y Wang - Digestive Diseases and Sciences, 2022 - Springer
Background With the rise of liquid biopsy in oncology, circulating miRNAs have become one
of the most promising noninvasive biomarkers for early detection of hepatocellular …