Synergistic effects of caffeine in combination with conventional drugs: perspectives of a drug that never ages

D Ialongo, V Tudino, M Arpacioglu, A Messore… - Pharmaceuticals, 2023 - mdpi.com
Plants have been known since ancient times for their healing properties, being used as
preparations against human diseases of different etiologies. More recently, natural products …

[HTML][HTML] Antiviral and anti-inflammatory drugs to combat COVID-19: Effects on cardiac ion channels and risk of ventricular arrhythmias

LX Cubeddu, D De la Rosa, M Ameruoso - BioImpacts: BI, 2022 - ncbi.nlm.nih.gov
Methods: We conducted a literature search on the drugs with purported or demonstrated
efficacy against COVID-19 disease, emphasizing the mechanisms by which anti-COVID-19 …

C60 fullerene enhances cisplatin anticancer activity and overcomes tumor cell drug resistance

S Prylutska, R Panchuk, G Gołuński, L Skivka… - Nano Research, 2017 - Springer
We formulated and analyzed a novel nanoformulation of the anticancer drug cisplatin (Cis)
with C 60 fullerene (C 60+ Cis complex) and showed its higher toxicity toward tumor cell …

Characterization of C 60 fullerene complexation with antibiotic doxorubicin

YI Prylutskyy, MP Evstigneev, IS Pashkova… - Physical Chemistry …, 2014 - pubs.rsc.org
The aim of this paper was to provide the physico-chemical characterization of a key process
leading to amplification of the antitumor effect of antibiotic Doxorubicin (Dox) in vivo and in …

New life of an old drug: Caffeine as a modulator of antibacterial activity of commonly used antibiotics

A Woziwodzka, M Krychowiak-Maśnicka, G Gołuński… - Pharmaceuticals, 2022 - mdpi.com
With the rapid and continuous emergence of antimicrobial resistance, bacterial infections
became a significant global healthcare concern. One of the proposed strategies to combat …

Fine-tuning recA expression in Staphylococcus aureus for antimicrobial photoinactivation: importance of photo-induced DNA damage in the photoinactivation …

M Grinholc, A Rodziewicz, K Forys… - Applied microbiology …, 2015 - Springer
Bacterial cell envelope is generally accepted as the primary target for a photo-induced
oxidative stress. It is plausible that DNA damage occurs during the antimicrobial …

Structural organization of C60 fullerene, doxorubicin, and their complex in physiological solution as promising antitumor agents

YI Prylutskyy, MP Evstigneev, VV Cherepanov… - Journal of Nanoparticle …, 2015 - Springer
Specific features of structural self-organization of C 60 fullerene (1 nm size range), antitumor
antibiotic doxorubicin (Dox) and their complex in physiological solution (0.9% NaCl) have …

Does C60 fullerene act as a transporter of small aromatic molecules?

A Borowik, Y Prylutskyy, Ł Kawelski, O Kyzyma… - Colloids and Surfaces B …, 2018 - Elsevier
C 60 fullerene is reported to directly interact with biomolecules, such as aromatic mutagens
or anticancer drugs. Therefore, it is extensively studied for its potential application in the …

Structural self-organization of C 60 and cisplatin in physiological solution

YI Prylutskyy, VV Cherepanov… - Physical Chemistry …, 2015 - pubs.rsc.org
The specific features of structural self-organization of C60 fullerene and antitumor drug
cisplatin (Cis) in physiological solution (0.9% NaCl) have been investigated by means of …

Interaction of ionic liquids with human serum albumin in the view of bioconcentration: a preliminary study

D Kowalska, S Stolte, D Wyrzykowski, P Stepnowski… - Chemical Papers, 2022 - Springer
Bioaccumulation potential is critical in PBT and risk assessment of chemicals. However, for
ionic liquids (ILs), this aspect remains neglected. It is especially important to fill this gap …