Importance Gastroesophageal reflux disease (GERD) is defined by recurrent and
troublesome heartburn and regurgitation or GERD-specific complications and affects …

Proton pump inhibitors (PPIs), long thought to be safe, are associated with a number of
nonkidney adverse health outcomes and several untoward kidney outcomes, including …

Background Immune checkpoint inhibitor-associated acute kidney injury (ICPi-AKI) has
emerged as an important toxicity among patients with cancer. Methods We collected data on …

Abstract Proton Pump Inhibitors are used widely to manage many gastric acid-related
conditions such as gastroesophageal disease, gastritis, esophagitis, Barrett's esophagus …

Previous epidemiological studies have raised the concern that the use of proton pump
inhibitors (PPIs) is associated with an increased risk of kidney diseases. To date, no …

Acute kidney injury is common among hospitalized individuals, particularly those exposed to
certain medications, and is associated with substantial morbidity and mortality. In a …

Since their approval by the Food and Drug Administration (FDA) in 1989, proton pump
inhibitors (PPIs) have become one of the most highly utilized drugs in the United States …

Proton pump inhibitors (PPIs) were widely used. Observational studies suggested
increasing risk of kidney injury in patients with PPIs treatment. We gathered six PPI regimens …

Tacrolimus is a calcineurin inhibitor used to prevent rejection in allogenic solid organ
transplant recipients, which is metabolized in the liver with cytochrome P450 isoforms 3A4 …

Proton pump inhibitors (PPIs) are widely prescribed in medical practice for the treatment of
several gastrointestinal disorders. Previous epidemiology studies have reported the …