The in vivo fate of polymeric micelles

Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

[HTML][HTML] Polymeric micellar systems—a special emphasis on “smart” drug delivery

I Negut, B Bita - Pharmaceutics, 2023 - mdpi.com
Concurrent developments in anticancer nanotechnological treatments have been observed
as the burden of cancer increases every year. The 21st century has seen a transformation in …

Nanomedicines and nanomaterials for cancer therapy: Progress, challenge and perspectives

Z Jing, Q Du, X Zhang, Y Zhang - Chemical Engineering Journal, 2022 - Elsevier
The field of nanomedicines and nanomaterials has been rapidly developing with several
considerable breakthroughs in the treatment of cancer. However, some challenges may …

Advanced and innovative nano-systems for anticancer targeted drug delivery

L Tang, J Li, Q Zhao, T Pan, H Zhong, W Wang - Pharmaceutics, 2021 - mdpi.com
The encapsulation of therapeutic agents into nano-based drug delivery system for cancer
treatment has received considerable attention in recent years. Advancements in …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B Xie, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Barrier permeation and improved nanomedicine delivery in tumor microenvironments

J Liu, J Zhang, Y Gao, Y Jiang, Z Guan, Y Xie, J Hu… - Cancer Letters, 2023 - Elsevier
Nanomedicines can effectively penetrate tumor sites compared to traditionally used drugs.
However, effective drugs that reach the interior of tumors remain limited. Based on studies of …

Combination therapy as a promising way to fight oral cancer

JPN Silva, B Pinto, L Monteiro, PMA Silva, H Bousbaa - Pharmaceutics, 2023 - mdpi.com
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …

Advances in the application of nanotechnology in reducing cardiotoxicity induced by cancer chemotherapy

X Su, X Zhang, W Liu, X Yang, N An, F Yang… - Seminars in Cancer …, 2022 - Elsevier
Advances in the development of anti-tumour drugs and related technologies have resulted
in a significant increase in the number of cancer survivors. However, the incidence of …

Reversible stimuli-responsive nanomaterials with on-off switching ability for biomedical applications

T Alejo, L Uson, M Arruebo - Journal of Controlled Release, 2019 - Elsevier
Many long-acting extended drug release systems can provide controlled or sustained
release of therapeutic payloads. In the majority of those systems drug release cannot be …

Recent progress on the synergistic antitumor effect of a borneol-modified nanocarrier drug delivery system

J Li, Q Xie, R Ma, Y Li, J Yuan, M Ren, H Li… - Frontiers in …, 2021 - frontiersin.org
Borneol, a traditional Chinese medicine, can enhance therapeutic efficacy by guiding the
active ingredients to the target site. Reportedly, borneol improves the penetration capacity of …