The papillomavirus family represents a remarkably heterogeneous group of viruses. At
present, 77 distinct genotypes have been identified in humans and partial sequences have …

Human papillomaviruses (HPVs) are small double‐stranded DNA viruses that infect the
cutaneous and mucosal epithelium. Infection by specific HPV types has been linked to the …

The papillomavirus E4 open reading frame (ORF) is contained within the E2 ORF, with the
primary E4 gene-product (E1∧ E4) being translated from a spliced mRNA that includes the …

Background Human papillomaviruses (HPV) are known to cause cancers of the cervix and
other anogenital tract sites. Molecular biology has provided some evidence as to the specific …

Bovine papillomaviruses (BPV) are DNA oncogenic viruses inducing hyperplastic benign
lesions of both cutaneous and mucosal epithelia in cattle. Ten (BPV 1-10) different viral …

Publisher Summary The chapter discusses the molecular and epidemiological aspects that
support the etiological role of Human Papillomaviruses (HPV) in cervical carcinogenesis …

HPV late gene expression is initiated as an infected basal cell migrates through the
differentiating layers of the epidermis, resulting in the onset of vegetative viral DNA …

The most highly expressed protein in the productive life cycle of human papillomaviruses
(HPVs) is E1∧ E4, but its function is not well understood. To investigate the role of E1∧ E4 …

ABSTRACT Human papillomavirus type 16 (HPV16) is the most common cause of cervical
carcinoma. Cervical cancer develops from low-grade lesions that support the productive …

Human papillomavirus E6 oncoproteins induce the proteasomal degradation of several multi-
PDZ (PSD95/Dlg/ZO-1) domain-containing proteins such as the human homologue of …