Cystic fibrosis: recent insights into inhaled antibiotic treatment and future perspectives

G Taccetti, M Francalanci, G Pizzamiglio, B Messore… - Antibiotics, 2021 - mdpi.com
Although new inhaled antibiotics have profoundly improved respiratory diseases in cystic
fibrosis (CF) patients, lung infections are still the leading cause of death. Inhaled antibiotics …

Burkholderia cenocepacia Infections in Cystic Fibrosis Patients: Drug Resistance and Therapeutic Approaches

VC Scoffone, LR Chiarelli, G Trespidi… - Frontiers in …, 2017 - frontiersin.org
Burkholderia cenocepacia is an opportunistic pathogen particularly dangerous for cystic
fibrosis (CF) patients. It can cause a severe decline in CF lung function possibly developing …

European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis

AB Chang, R Fortescue, K Grimwood… - European …, 2021 - Eur Respiratory Soc
There is increasing awareness of bronchiectasis in children and adolescents, a chronic
pulmonary disorder associated with poor quality of life for the child/adolescent and their …

Characterization of microbiota in endometrial fluid and vaginal secretions in infertile women with repeated implantation failure

K Kitaya, Y Nagai, W Arai, Y Sakuraba… - Mediators of …, 2019 - Wiley Online Library
Studies suggest that persisting intrauterine bacterial infectious conditions such as chronic
endometritis potentially impair the embryo implantation process. The microbial environment …

A structure-based classification of class A β-lactamases, a broadly diverse family of enzymes

A Philippon, P Slama, P Dény… - Clinical microbiology …, 2016 - Am Soc Microbiol
For medical biologists, sequencing has become a commonplace technique to support
diagnosis. Rapid changes in this field have led to the generation of large amounts of data …

Burkholderia cepacia complex infections: more complex than the bacterium name suggest

MM Sfeir - Journal of Infection, 2018 - Elsevier
Burkholderia cepacia complex (Bcc) is an emerging pathogen causes life-threatening
infections in cystic fibrosis patients. This narrative review aims to highlight an update on the …

[HTML][HTML] Standards for the care of people with cystic fibrosis (CF); recognising and addressing CF health issues

PR Burgel, KW Southern, C Addy, A Battezzati… - Journal of Cystic …, 2024 - Elsevier
This is the third in a series of four papers updating the European Cystic Fibrosis Society
(ECFS) standards for the care of people with CF. This paper focuses on recognising and …

Antibacterial Activity of a Natural Clay Mineral against Burkholderia cepacia Complex and Other Bacterial Pathogens Isolated from People with Cystic Fibrosis

S Behroozian, JEA Zlosnik, W Xu, LY Li, JE Davies - Microorganisms, 2023 - mdpi.com
There is an impending crisis in healthcare brought about by a new era of untreatable
infections caused by bacteria resistant to all available antibiotics. Thus, there is an urgent …

Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic …

KM Papp-Wallace, SA Becka, ET Zeiser… - ACS infectious …, 2017 - ACS Publications
Burkholderia multivorans is a significant health threat to persons with cystic fibrosis (CF).
Infections are difficult to treat as this pathogen is inherently resistant to multiple antibiotics …

[68Ga]Ga-Ornibactin for Burkholderia cepacia complex Infection Imaging Using Positron Emission Tomography

K Bendova, V Raclavsky, R Novotny… - Journal of Medicinal …, 2023 - ACS Publications
Bacteria from the Burkholderia cepacia complex are generally considered to be non-
pathogenic to the healthy population. However, some of these species may cause serious …