Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for pulmonary application: a review of the state of the art

S Weber, A Zimmer, J Pardeike - European Journal of Pharmaceutics and …, 2014 - Elsevier
Drug delivery by inhalation is a noninvasive means of administration that has following
advantages for local treatment for airway diseases: reaching the epithelium directly …

Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Solid lipid nanoparticles for oral drug delivery: chitosan coating improves stability, controlled delivery, mucoadhesion and cellular uptake

Y Luo, Z Teng, Y Li, Q Wang - Carbohydrate polymers, 2015 - Elsevier
The poor stability of solid lipid nanoparticles (SLN) under acidic condition resulted in large
aggregation in gastric environment, limiting their application as oral delivery systems. In this …

[HTML][HTML] Recent progress of lipid nanoparticles-based lipophilic drug delivery: focus on surface modifications

Y Seo, H Lim, H Park, J Yu, J An, HY Yoo, T Lee - Pharmaceutics, 2023 - mdpi.com
Numerous drugs have emerged to treat various diseases, such as COVID-19, cancer, and
protect human health. Approximately 40% of them are lipophilic and are used for treating …

[HTML][HTML] Solid lipid nanoparticles: multitasking nano-carriers for cancer treatment

J German-Cortés, M Vilar-Hernández, D Rafael… - Pharmaceutics, 2023 - mdpi.com
Despite all the advances seen in recent years, the severe adverse effects and low specificity
of conventional chemotherapy are still challenging problems regarding cancer treatment …

[HTML][HTML] Overview of P-glycoprotein inhibitors: a rational outlook

KMR Srivalli, PK Lakshmi - Brazilian Journal of Pharmaceutical …, 2012 - SciELO Brasil
P-glycoprotein (P-gp), a transmembrane permeability glycoprotein, is a member of ATP
binding cassette (ABC) super family that functions specifically as a carrier mediated primary …

Chitosan coated nanostructured lipid carriers for brain delivery of proteins by intranasal administration

O Gartziandia, E Herran, JL Pedraz, E Carro… - Colloids and Surfaces B …, 2015 - Elsevier
The remarkable increase in the prevalence of neurodegenerative diseases has become a
serious public health problem. Considering the lack of effective treatments to address these …

The influence of nanoparticulate drug delivery systems in drug therapy

N Aminu, I Bello, NM Umar, N Tanko, A Aminu… - Journal of drug delivery …, 2020 - Elsevier
The advancement in medical sciences and perturbing limitations of some conventional drug
delivery systems have triggered extensive research in nanomedicine, and there have been …

Novel formulation approaches for optimising delivery of anticancer drugs based on P-glycoprotein modulation

T Bansal, N Akhtar, M Jaggi, RK Khar… - Drug discovery today, 2009 - Elsevier
Considerable research efforts have been directed towards understanding the enigma of P-
glycoprotein (P-gp) in drug development and delivery. P-gp is a multi-specific drug efflux …

Respirable nanocarriers as a promising strategy for antitubercular drug delivery

MM Mehanna, SM Mohyeldin, NA Elgindy - Journal of controlled release, 2014 - Elsevier
Tuberculosis is considered a fatal respiratory infectious disease that represents a global
threat, which must be faced. Despite the availability of oral conventional anti-tuberculosis …