The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

Vascular endothelial growth factor (VEGF) has a crucial role in the angiogenesis of various
tumors, including glioma. As the levels of VEGF would change in patients with glioma, we …

Abstract Wilms' tumor 1-associating protein (WTAP) interacts with the Wilms' tumor 1 gene.
Although originally classified as a tumor suppressor, WTAP was later found to be over …

Tumor progression, limited efficacy of current standard treatments, and the rise in patient
mortality are associated with gene expression caused by the synergistic action of …

VEGF is an important factor in tumor vascularization and used as target for anti‐angiogenic
treatment strategies in glioma. In this study, we demonstrate for the first time that VEGF is a …

Oxygen deficiency is one of the key pathogenetic factors determining development and
severity of many diseases, including inflammatory, infectious diseases, and cancer. Lack of …

As a key hub of malignant properties, the cancer microenvironment plays a crucial role
intimately connected to tumor properties. Accumulating evidence supports that the …

Glioblastomas are the most aggressive type of brain tumour, with poor prognosis even after
standard treatment such as surgical resection, temozolomide and radiation therapy. The …

To evaluate the association between a vessel size index (VSIMRI) derived from dynamic
susceptibility contrast (DSC) perfusion imaging using a custom spin-and-gradient echo …

Glioblastoma multiforme (GBM) is a highly proliferative and locally invasive cancer with poor
prognosis and a high recurrence rate. Although anti-VEGF (vascular endothelial growth …