The application of bioreactors for cartilage tissue engineering: advances, limitations, and future perspectives

L Fu, P Li, H Li, C Gao, Z Yang, T Zhao… - Stem cells …, 2021 - Wiley Online Library
Tissue engineering (TE) has brought new hope for articular cartilage regeneration, as TE
can provide structural and functional substitutes for native tissues. The basic elements of TE …

Differentiation of stem cells into chondrocytes and their potential clinical application in cartilage regeneration

J Cieśla, M Tomsia - Histochemistry and Cell Biology, 2025 - Springer
Cartilage diseases and injuries are considered difficult to treat owing to the low regenerative
capacity of this tissue. Using stem cells (SCs) is one of the potential methods of treating …

Effect of micro-strain stress on in vitro proliferation and functional expression of human osteoarthritic chondrocytes

B Zhao, J Ma, J He, X Ma - Journal of Orthopaedic Surgery and Research, 2022 - Springer
Background This study aimed to analyze the in vitro effect of micro-strain stress on the
proliferation and functional marker expression in chondrocytes isolated from human …

AGAROSE-COLLAGEN HYDROGEL COMPOSITIONS IMPACT MATRIX MECHANICS AND EXTRACELLULAR DEPOSITION

CM Zigan - 2023 - hammer.purdue.edu
To elucidate the mechanisms of cellular mechanotransduction, it is necessary to employ
biomaterials that effectively merge biofunctionality with appropriate mechanical …