Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …

Macrophages phagocytize pathogens to initiate innate immunity and products from the
tumor microenvironment (TME) to mediate tumor immunity. The loss of tumor-associated …

Mapping tumor metabolic remodeling and their spatial crosstalk with surrounding non-tumor
cells can fundamentally improve our understanding of tumor biology, facilitates the …

Reinvigoration of antitumor immunity remains an unmet challenge. Our retrospective
analyses revealed that cancer patients who took antihistamines during immunotherapy …

Neutrophils are specialized innate cells that require constant replenishment from
proliferative bone marrow (BM) precursors as a result of their short half-life. Although it is …

Early cancer detection greatly increases the chances for successful treatment, but available
diagnostics for some tumours, including lung adenocarcinoma (LA), are limited. An ideal …

High-performance metabolic analysis is emerging in the diagnosis and prognosis of breast
cancer (BrCa). Still, advanced tools are in demand to deliver the application potentials of …

Neutrophils are indispensable antagonists of microbial infection and facilitators of wound
healing. In the cancer setting, a newfound appreciation for neutrophils has come into view …

Inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, and
leukotrienes, impact the immune system, usually as proinflammatory factors. Other …

Macrophages are strategically located throughout the body tissues, where they ingest and
process foreign materials, dead cells and debris and recruit additional macrophages in …