Immunological mechanisms underlying clinical phenotypes and noninvasive diagnosis of immune checkpoint inhibitor‐induced kidney disease

H Seethapathy, K Mistry, ME Sise - Immunological Reviews, 2023 - Wiley Online Library
Immune checkpoint inhibitors (ICIs) have become a mainstay of cancer therapy, with over 80
FDA‐approved indications. Used in a variety of settings and in combination with each other …

Non-pharmaceutical interventions to optimize cancer immunotherapy

M Boesch, F Baty, F Rassouli, T Kowatsch… - …, 2023 - Taylor & Francis
The traditional picture of cancer patients as weak individuals requiring maximum rest and
protection is beginning to dissolve. Too much focus on the medical side and one's own …

Diagnosis and management of immune checkpoint inhibitor–associated nephrotoxicity: a position statement from the American Society of Onco-nephrology

SM Herrmann, A Abudayyeh, S Gupta, P Gudsoorkar… - Kidney international, 2025 - Elsevier
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer and are now
the backbone of therapy for several malignancies. However, ICIs can cause a spectrum of …

Immune checkpoint inhibitor–associated nephritis—treatment standard

EB Barbir, A Kitchlu… - Nephrology Dialysis …, 2024 - academic.oup.com
Over the last 13 years, the use of immune checkpoint inhibitor (ICI) therapy has grown
remarkably, owing to their unprecedented anti-tumor efficacy in certain tumor groups. With …

Chronic immune-related adverse events arising from immune checkpoint inhibitors: an update

K Fletcher, DB Johnson - Journal for Immunotherapy of …, 2024 - pmc.ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) have transformed cancer treatment, improving outcomes
for many patients. However, toxicities termed immune-related adverse events (irAEs) are …

Onconephrology 2022: an update

M Bonilla, P Gudsoorkar, R Wanchoo, SM Herrmann… - Kidney360, 2023 - journals.lww.com
Onconephrology is an upcoming and expanding subspecialty that deals with the
intersections between hematology/oncology and nephrology. With the paradigm shift in the …

Immune-related acute kidney injury in Australian non-small cell lung cancer patients: real-world results

A Knox, T Cloney, H Janssen, BJ Solomon… - Lung Cancer, 2023 - Elsevier
Background The use of immune checkpoint inhibitors has altered therapeutic paradigms in
NSCLC. However, they may cause immune-related toxicities, including acute kidney injury …

Updates in toxicities associated with immune checkpoint inhibitors

NB Curkovic, DB Johnson - Expert Review of Clinical Immunology, 2023 - Taylor & Francis
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) have become a pillar of
treatment for numerous cancers with increasing use in combination with other ICIs and in …

Immune checkpoint inhibitor induced nephrotoxicity: an ongoing challenge

M Catalano, G Roviello, IC Galli, R Santi… - Frontiers in Medicine, 2022 - frontiersin.org
Although immune checkpoint inhibitors (ICIs) have dramatically revolutionized the field of
oncology over the last decade, severe immune-related adverse events (irAEs) are …

Immune checkpoint inhibitor–associated AKI: debates in diagnosis, management, and rechallenge

H Seethapathy, SM Herrmann, A Rashidi - Seminars in nephrology, 2022 - Elsevier
Immune checkpoint inhibitors (ICIs) are now established treatments for advanced cancer
and their use is now ubiquitous. The high upside of ICIs is tempered by their toxicity profile …