The traditional picture of cancer patients as weak individuals requiring maximum rest and protection is beginning to dissolve. Too much focus on the medical side and one's own …
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer and are now the backbone of therapy for several malignancies. However, ICIs can cause a spectrum of …
Over the last 13 years, the use of immune checkpoint inhibitor (ICI) therapy has grown remarkably, owing to their unprecedented anti-tumor efficacy in certain tumor groups. With …
K Fletcher, DB Johnson - Journal for Immunotherapy of …, 2024 - pmc.ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) have transformed cancer treatment, improving outcomes for many patients. However, toxicities termed immune-related adverse events (irAEs) are …
Onconephrology is an upcoming and expanding subspecialty that deals with the intersections between hematology/oncology and nephrology. With the paradigm shift in the …
A Knox, T Cloney, H Janssen, BJ Solomon… - Lung Cancer, 2023 - Elsevier
Background The use of immune checkpoint inhibitors has altered therapeutic paradigms in NSCLC. However, they may cause immune-related toxicities, including acute kidney injury …
NB Curkovic, DB Johnson - Expert Review of Clinical Immunology, 2023 - Taylor & Francis
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) have become a pillar of treatment for numerous cancers with increasing use in combination with other ICIs and in …
M Catalano, G Roviello, IC Galli, R Santi… - Frontiers in Medicine, 2022 - frontiersin.org
Although immune checkpoint inhibitors (ICIs) have dramatically revolutionized the field of oncology over the last decade, severe immune-related adverse events (irAEs) are …
H Seethapathy, SM Herrmann, A Rashidi - Seminars in nephrology, 2022 - Elsevier
Immune checkpoint inhibitors (ICIs) are now established treatments for advanced cancer and their use is now ubiquitous. The high upside of ICIs is tempered by their toxicity profile …