In-silico screening of missense nsSNPs in Delta-opioid receptor protein and their restoring tendency on MCRT interaction; focusing on dynamic nature

JP Simon, S Dong - International Journal of Biological Macromolecules, 2024 - Elsevier
Delta-opioid receptor protein (OPRD1) is one of the potential targets for treating pain. The
presently available opioid agonists are known to cause unnecessary side effects. To …

Pharmacoinformatics approach for type 2 diabetes mellitus therapeutics using phytocompounds from Costus genus: an in-silico investigation

D Bhavsar, S Kutre, P Shikhare, S Kumar… - Journal of …, 2024 - Taylor & Francis
Abstract Type 2 Diabetes Mellitus (T2DM), as a significant health concern globally,
particularly in India, underscoring the vital need for effective therapeutics. Current drug …