Sex-specific differences in glioblastoma

A Carrano, JJ Juarez, D Incontri, A Ibarra, HG Cazares - Cells, 2021 - mdpi.com
Sex differences have been well identified in many brain tumors. Even though glioblastoma
(GBM) is the most common primary malignant brain tumor in adults and has the worst …

Combining molecular and imaging metrics in cancer: radiogenomics

R Lo Gullo, I Daimiel, EA Morris, K Pinker - Insights into imaging, 2020 - Springer
Background Radiogenomics is the extension of radiomics through the combination of
genetic and radiomic data. Because genetic testing remains expensive, invasive, and time …

Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data

W Yang, NM Warrington, SJ Taylor… - Science translational …, 2019 - science.org
Sex differences in the incidence and outcome of human disease are broadly recognized but,
in most cases, not sufficiently understood to enable sex-specific approaches to treatment …

Imaging signatures of glioblastoma molecular characteristics: a radiogenomics review

A Fathi Kazerooni, S Bakas… - Journal of Magnetic …, 2020 - Wiley Online Library
Over the past few decades, the advent and development of genomic assessment methods
and computational approaches have raised the hopes for identifying therapeutic targets that …

[HTML][HTML] A nomogram based on bi-regional radiomics features from multimodal magnetic resonance imaging for preoperative prediction of microvascular invasion in …

R Zhang, L Xu, X Wen, J Zhang, P Yang… - … Imaging in Medicine …, 2019 - ncbi.nlm.nih.gov
Background We aimed to develop and validate a nomogram combining bi-regional
radiomics features from multimodal magnetic resonance imaging (MRI) and …

Imaging genomics in cancer research: limitations and promises

HX Bai, AM Lee, L Yang, P Zhang… - The British journal of …, 2016 - academic.oup.com
Recently, radiogenomics or imaging genomics has emerged as a novel high-throughput
method of associating imaging features with genomic data. Radiogenomics has the potential …

Introduction to radiomics and radiogenomics in neuro-oncology: implications and challenges

N Beig, K Bera, P Tiwari - Neuro-Oncology Advances, 2020 - academic.oup.com
Neuro-oncology largely consists of malignancies of the brain and central nervous system
including both primary as well as metastatic tumors. Currently, a significant clinical …

Multicenter imaging outcomes study of The Cancer Genome Atlas glioblastoma patient cohort: imaging predictors of overall and progression-free survival

P Wangaryattawanich, M Hatami, J Wang… - Neuro …, 2015 - academic.oup.com
Background Despite an aggressive therapeutic approach, the prognosis for most patients
with glioblastoma (GBM) remains poor. The aim of this study was to determine the …

Learning MRI-based classification models for MGMT methylation status prediction in glioblastoma

VG Kanas, EI Zacharaki, GA Thomas, PO Zinn… - Computer methods and …, 2017 - Elsevier
Abstract Background and Objective The O 6-methylguanine-DNA-methyltransferase (MGMT)
promoter methylation has been shown to be associated with improved outcomes in patients …

Radiomics in brain tumors: an emerging technique for characterization of tumor environment

A Kotrotsou, PO Zinn, RR Colen - Magnetic Resonance Imaging …, 2016 - mri.theclinics.com
Brain tumor is the growth of abnormal cells in the brain and ranges from noncancerous
(benign) to malignant. Glioblastoma (GBM) is the most aggressive type of brain tumor, rising …