Molecular and metabolic regulation of immunosuppression in metastatic pancreatic ductal adenocarcinoma

SK Gautam, SK Batra, M Jain - Molecular cancer, 2023 - Springer
Immunosuppression is a hallmark of pancreatic ductal adenocarcinoma (PDAC),
contributing to early metastasis and poor patient survival. Compared to the localized tumors …

Exosome-derived noncoding RNAs: Function, mechanism, and application in tumor angiogenesis

K Yang, Q Zhou, B Qiao, B Shao, S Hu, G Wang… - … Therapy-Nucleic Acids, 2022 - cell.com
Exosomes are extracellular vesicles released by various cell types that perform various
biological functions, mainly mediating communication between different cells, especially …

Progress in genome-wide identification of RBPs and their role in mitigating stresses, and growth in plants

M Haroon, H Tariq, R Afzal, M Anas, S Nasar… - South African Journal of …, 2023 - Elsevier
Recent ribonomics research has shed light on thousands of RNA Binding Proteins (RBPs)
that regulate post-transcriptional changes critical to plant development, growth, and …

[HTML][HTML] Early diagnosis of pancreatic cancer: What strategies to avoid a foretold catastrophe

V Tonini, M Zanni - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
While great strides in improving survival rates have been made for most cancers in recent
years, pancreatic ductal adenocarcinoma (PDAC) remains one of the solid tumors with the …

Genetics, genomics and emerging molecular therapies of pancreatic cancer

J Liu, M Mroczek, A Mach, M Stępień, A Aplas… - Cancers, 2023 - mdpi.com
Simple Summary This review article is a summary of the current state of knowledge
regarding the genetics of pancreatic cancer and a presentation of possible treatment options …

Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma

F Rezagholizadeh, F Tajik, M Talebi, SR Taha… - Frontiers in …, 2024 - frontiersin.org
Introduction Pancreatic cancer is a truculent disease with limited treatment options and a
grim prognosis. Immunotherapy has shown promise in treating various types of cancer, but …

Annotation and functional characterization of long noncoding RNAs deregulated in pancreatic adenocarcinoma

VF da Paixão, OJ Sosa, DV da Silva Pellegrina… - Cellular Oncology, 2022 - Springer
Purpose Transcriptome analysis of pancreatic ductal adenocarcinoma (PDAC) has been
useful to identify gene expression changes that sustain malignant phenotypes. Yet, most …

Oncogenomic changes in pancreatic cancer and their detection in stool

H Sammallahti, VK Sarhadi, A Kokkola, R Ghanbari… - Biomolecules, 2022 - mdpi.com
Pancreatic cancer (PC) is an aggressive malignancy with a dismal prognosis. To improve
patient survival, the development of screening methods for early diagnosis is pivotal …

Unlocking the potential of exosomes in cancer research: A paradigm shift in diagnosis, treatment, and prevention

S Khoushab, MH Aghmiuni, N Esfandiari… - … -Research and Practice, 2024 - Elsevier
Exosomes, which are tiny particles released by cells, have the ability to transport various
molecules, including proteins, lipids, and genetic material containing non-coding RNAs …

LINC00960 regulates cell proliferation and glycolysis in pancreatic cancer through the miR‐326‐3p/TUFT1/AKT–mTOR axis

B Zhou, JH Lei, Q Wang, TF Qu, LC Cha… - … Journal of Medical …, 2022 - Wiley Online Library
Pancreatic cancer (PC) is a common malignant cancer characterized by high mortality and
poor prognosis. LINC00690 was involved in the occurrence and progression of PC, but the …