As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …

Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …

Grafted mesenchymal stem cells (MSCs) yield neuroprotection in preclinical stroke models
by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has …

Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

Background: Ferroptosis is a form of iron-dependent programmed cell death that differs from
apoptosis with regards to both mechanism and cell morphology. Therefore, ferroptotic-based …

Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

In addition to the devastating symptoms of dementia, Alzheimer's disease (AD) is
characterized by accumulation of the processing products of the amyloid-β (Aβ) peptide …

Manganese (Mn) is the twelfth most abundant element on the earth and an essential metal
to human health. Mn is present at low concentrations in a variety of dietary sources, which …

Background Although prior studies showed a correlation between environmental
manganese (Mn) exposure and neurodevelopmental disorders in children, the results have …

Introduction Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's
disease, Huntington's disease, amyotrophic lateral sclerosis and prion disease represent …