Materials and Methods Searches of the MEDLINE and Cochrane CENTRAL databases from
January 1968 to December 2008 were performed by both authors using the following search …

In cardiovascular surgery, reduced organ perfusion and oxygen delivery contribute to
increased postoperative morbidity and prolonged intensive care unit stay. Goal-directed …

Organ dysfunction and multiple organ failure are the main causes of prolonged hospital stay
after cardiac surgery, which increases resource use and health care costs. Increased levels …

Early goal-directed therapy is a term used to describe the guidance of intravenous fluid and
vasopressor/inotropic therapy by using cardiac output or similar parameters in the …

This randomized, double-blind trial was designed to determine the benefit of high and
cumulative doses of flunisolide added to salbutamol in patients with acute asthma in the …

Background. Reduction in oxygen delivery can lead to organ dysfunction and death by
cellular hypoxia, detectable by progressive (mixed) venous oxyhemoglobin desaturation …

Patients with acute brain injury (ABI) often require the application of positive end-expiratory
pressure (PEEP) to optimize mechanical ventilation and systemic oxygenation. However, the …

The resident internal medicine called from the Emergency Department (ED).“Can you
please come and see my patient, I think he is becoming septic and needs admission to …

OBJECTIVE: To assess the association between postoperative central venous oxygen
saturation (ScvO2) and arterial lactate with outcome after cardiac surgery. DESIGN …

Goal-directed therapy (GDT) encompasses guidance of intravenous (IV) fluid and
vasopressor/inotropic therapy by cardiac output or similar parameters to help in early …