Epstein-Barr virus and neurological diseases

N Zhang, Y Zuo, L Jiang, Y Peng, X Huang… - Frontiers in Molecular …, 2022 - frontiersin.org
Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA
virus that is ubiquitous in 90–95% of the population as a gamma herpesvirus. It exists in two …

Genes of the ubiquitin proteasome system qualify as differential markers in malignant glioma of astrocytic and oligodendroglial origin

J Vriend, T Klonisch - Cellular and Molecular Neurobiology, 2023 - Springer
We have mined public genomic datasets to identify genes coding for components of the
ubiquitin proteasome system (UPS) that may qualify as potential diagnostic and therapeutic …

Generation of glioblastoma in mice engrafted with human cytomegalovirus-infected astrocytes

J Guyon, S Haidar Ahmad, R El Baba… - Cancer Gene …, 2024 - nature.com
Mounting evidence is identifying human cytomegalovirus (HCMV) as a potential oncogenic
virus. HCMV has been detected in glioblastoma multiforme (GB). Herewith, we present the …

Glioblastoma as a Novel Drug Repositioning Target: Updated State

H Hosseinalizadeh, A Ebrahimi… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Glioblastoma multiforme (GBM) is an aggressive form of adult brain tumor that can arise from
a low-grade astrocytoma. In recent decades, several new conventional therapies have been …

Disease burden, risk factors, and trends of primary central nervous system (CNS) cancer: a global study of registries data

J Huang, SC Chan, V Lok, L Zhang, X Lin… - Neuro …, 2023 - academic.oup.com
Background This study aimed to evaluate the global incidence, mortality, associated risk
factors, and temporal trends of central nervous system (CNS) cancer by sex, age, and …

Prognosis of EBV-positive gastric cancer with lymphoid stroma: systematic review and meta-analysis

T Ying, J Chen, J Song, Y Zhou, B Bao… - Scandinavian Journal …, 2024 - Taylor & Francis
Background Although gastric cancer with lymphoid stroma (GCLS) presents better
prognosis, uncertainty still exists regarding the association of Epstein-Barr virus (EBV) …

Genomic landscape of glioblastoma without IDH somatic mutation in 42 cases: a comprehensive analysis using RNA sequencing data

T Okamoto, R Mizuta, Y Takahashi, Y Otani… - Journal of Neuro …, 2024 - Springer
Purpose Glioblastoma is a malignant brain tumor with a poor prognosis. Genetic mutations
associated with this disease are complex are not fully understood and require further …

Epstein–Barr Virus: Emerging and Re-emerging Viral Infectious Diseases

B Sharma, U Sharma, D Raina, R Sharma… - Emerging Human Viral …, 2024 - Springer
Abstract The Epstein–Barr virus (EBV), also referred to as the human herpesvirus, is a
herpes virus. It ranks among the most common viruses that affect people. The majority of …

Unmasking Epstein-Barr Role in Gastric Carcinogenesis: A Gene Expression Approach to Virus-Positive Tumors

VC Santos da Silva, D Pereira, DS Avelar, JMC Silva… - bioRxiv, 2025 - biorxiv.org
Human gammaherpesvirus 4 or Epstein-Barr virus (EBV) is an oncogenic virus linked to
malignancies like gastric adenocarcinoma. Notably, EBV infection induces genetic and …

Overall patient's survival of glioblastoma associated to molecular markers: a pan-proteomic prospective study

L Drelich, M Duhamel, M Wisztorski, S Aboulouard… - bioRxiv, 2020 - biorxiv.org
Molecular heterogeneities are a key feature of glioblastoma (GBM) pathology impeding
patient's stratification and leading to high discrepancies between patients mean survivals …