[HTML][HTML] The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease

JN van der Veen, JP Kennelly, S Wan, JE Vance… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant
phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co …

Phospholipid synthesis and transport in mammalian cells

JE Vance - Traffic, 2015 - Wiley Online Library
Membranes of mammalian subcellular organelles contain defined amounts of specific
phospholipids that are required for normal functioning of proteins in the membrane. Despite …

Phosphatidylethanolamine metabolism in health and disease

E Calzada, O Onguka, SM Claypool - … review of cell and molecular biology, 2016 - Elsevier
Phosphatidylethanolamine (PE) is the second most abundant glycerophospholipid in
eukaryotic cells. The existence of four only partially redundant biochemical pathways that …

Ethanolamine and phosphatidylethanolamine: partners in health and disease

D Patel, SN Witt - Oxidative medicine and cellular longevity, 2017 - Wiley Online Library
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian
cells. PE comprises about 15–25% of the total lipid in mammalian cells; it is enriched in the …

Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells

JE Vance, G Tasseva - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2013 - Elsevier
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related
membrane aminophospholipids. In mammalian cells, PS is required for targeting and …

The Kennedy pathway—De novo synthesis of phosphatidylethanolamine and phosphatidylcholine

F Gibellini, TK Smith - IUBMB life, 2010 - Wiley Online Library
The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE)
account for greater than 50% of the total phospholipid species in eukaryotic membranes and …

The role of nonbilayer phospholipids in mitochondrial structure and function

W Basu Ball, JK Neff, VM Gohil - FEBS letters, 2018 - Wiley Online Library
Mitochondrial structure and function are influenced by the unique phospholipid composition
of its membranes. While mitochondria contain all the major classes of phospholipids, recent …

Phosphatidylethanolamine deficiency in Mammalian mitochondria impairs oxidative phosphorylation and alters mitochondrial morphology

G Tasseva, HD Bai, M Davidescu, A Haromy… - Journal of Biological …, 2013 - ASBMB
Mitochondrial dysfunction is implicated in neurodegenerative, cardiovascular, and metabolic
disorders, but the role of phospholipids, particularly the nonbilayer-forming lipid …

Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis

M Bohdanowicz, S Grinstein - Physiological reviews, 2013 - journals.physiology.org
Endocytosis, phagocytosis, and macropinocytosis are fundamental processes that enable
cells to sample their environment, eliminate pathogens and apoptotic bodies, and regulate …

Stability, delivery and functions of human sperm RNAs at fertilization

E Sendler, GD Johnson, S Mao… - Nucleic acids …, 2013 - academic.oup.com
Increasing attention has focused on the significance of RNA in sperm, in light of its
contribution to the birth and long-term health of a child, role in sperm function and diagnostic …