[HTML][HTML] Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
High-density lipoproteins, reverse cholesterol transport and atherogenesis
HJ Pownall, C Rosales, BK Gillard… - Nature Reviews …, 2021 - nature.com
Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …
Apolipoprotein A1 infusions and cardiovascular outcomes after acute myocardial infarction
Background Cardiovascular events frequently recur after acute myocardial infarction, and
low cholesterol efflux—a process mediated by apolipoprotein A1, which is the main protein …
low cholesterol efflux—a process mediated by apolipoprotein A1, which is the main protein …
HDL in the 21st century: a multifunctional roadmap for future HDL research
A Rohatgi, M Westerterp, A Von Eckardstein… - Circulation, 2021 - Am Heart Assoc
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer
Circulating biomarkers have a great potential in diagnosing cancer diseases at early stages,
where curative treatment is a realistic possibility. In the recent years, using extracellular …
where curative treatment is a realistic possibility. In the recent years, using extracellular …
Lipid management in patients with chronic kidney disease
An increased risk of cardiovascular disease, independent of conventional risk factors, is
present even at minor levels of renal impairment and is highest in patients with end-stage …
present even at minor levels of renal impairment and is highest in patients with end-stage …
Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis
Atherosclerosis is a chronic inflammatory disease driven by lipid accumulation in arteries,
leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is …
leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is …
Myocardial infarction—From atherosclerosis to thrombosis: Uncovering new diagnostic and therapeutic approaches
J Palasubramaniam, X Wang… - … , thrombosis, and vascular …, 2019 - Am Heart Assoc
One of the earliest and best-recognized elements of atherosclerosis is its close relationship
with circulating LDL (low-density lipoprotein). There is convincing evidence that LDL …
with circulating LDL (low-density lipoprotein). There is convincing evidence that LDL …
Anti-inflammatory effects of HDL (high-density lipoprotein) in macrophages predominate over proinflammatory effects in atherosclerotic plaques
Objective: HDL (high-density lipoprotein) infusion reduces atherosclerosis in animal models
and is being evaluated as a treatment in humans. Studies have shown either anti-or …
and is being evaluated as a treatment in humans. Studies have shown either anti-or …
[HTML][HTML] Lipid rafts as a therapeutic target: thematic review series: biology of lipid rafts
D Sviridov, N Mukhamedova, YI Miller - Journal of lipid research, 2020 - ASBMB
Lipid rafts regulate the initiation of cellular metabolic and signaling pathways by organizing
the pathway components in ordered microdomains on the cell surface. Cellular responses …
the pathway components in ordered microdomains on the cell surface. Cellular responses …