Conspectus Much like linear, branched, and cyclic alkanes, condensed phosphates exist as
linear, branched, and cyclic structures. Inasmuch as alkanes are the cornerstone of organic …

The analysis of myo-inositol phosphates (InsPs) and myo-inositol pyrophosphates (PP-
InsPs) is a daunting challenge due to the large number of possible isomers, the absence of …

The inositol pyrophosphates (PP-InsPs) are a unique group of intracellular messengers that
represent some of the most highly phosphorylated molecules in nature. Genetic perturbation …

The free energy of nucleotide hydrolysis depends on phosphate concentration. Cells
regulate cytosolic phosphate levels by orchestrating phosphate acquisition and storage …

Diphospho-myo-inositol polyphosphates, also termed inositol pyrophosphates, are
molecular messengers containing at least one high-energy phosphoanhydride bond and …

We have investigated the continuous flow photooxidation of several conjugated dienes and
subsequent rearrangement using a practical and safe continuous-flow homemade …

Nudix hydrolases attract considerable attention for their wide range of specialized activities
in all domains of life. One particular group of Nudix phosphohydrolases (DIPPs), through …

Among many cellular functions, inositol pyrophosphates (PP-InsPs) are metabolic
messengers involved in the regulation of glucose uptake, insulin sensitivity, and weight gain …

Phosphate esters and anhydrides are abundant motifs in biologically important molecules.
Their chemical synthesis, modification, and purification are still challenging tasks often …

The multitudinous inositol phosphate family elicits a wide range of molecular effects that
regulate countless biological responses. In this review, I provide a methodological viewpoint …