Proper function of the vascular endothelium is essential for cardiovascular health, in large
part due to its antiproliferative, antihypertrophic, and anti‐inflammatory properties. Crucial to …

20-HETE (20-hydroxyeicosatetraenoic acid), a vasoconstrictor metabolite of arachidonic
acid formed through the action of CYP4A (cytochrome P450-4A) in vascular smooth muscle …

Objective Chronic presentation of the MS is associated with an increased likelihood for
stroke and poor stroke outcomes following occlusive cerebrovascular events. However, the …

Objectives: We aimed to assess whether a 7-day high-salt (HS) diet affects endothelium-
dependent and/or endothelium-independent microvascular function in the absence of …

BACKGROUND This study examined the vasoprotective role of circulating angiotensin II
(ANG II) levels in the cerebral circulation of high salt (HS)–fed (SS. BN-(D13hmgc41 …

Objectives This study sought to determine whether salt‐induced ANG II suppression
contributes to impaired CBF autoregulation. Methods Cerebral autoregulation was …

Obesity increases plasma renin activity and angiotensin II levels, leading to vascular
damage, elevated blood pressure, diabetes mellitus, and renal damage. Because genetic …

This study aimed to investigate the specific role of nitric oxide (NO) in micro-and
macrovascular response to a 7-day high-salt (HS) diet, specifically by measuring skin …

Resistant hypertension (RH) is a clinical condition in which the hypertensive patient has
become resistant to drug therapy and is often associated with increased cardiovascular …

A 3.7-Mb region of rat chromosome 13 (45.2–49.0 Mb) affects blood pressure (BP) in
females only, indicating the presence of sex-specific BP loci in close proximity to the Renin …