Metastasis is the most complex and deadly event. Tumor-stromal interface is a place where
invasion of tumor cells in the form of single-cell or collective migration occurs, with the latter …

Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Epithelial-derived high-grade serous ovarian cancer (HGSOC) is the deadliest gynecologic
malignancy. Roughly 80% of patients are diagnosed with late-stage disease, which is …

The clustered regularly interspaced short palindromic repeats system has demonstrated
considerable advantages over other nuclease-based genome editing tools due to its high …

Analyses of several databases showed that the lncRNA RNF157 Antisense RNA 1 (RNF157-
AS1) is overexpressed in epithelial ovarian cancer (EOC) tissues. In our study, suppressing …

Ovarian cancer is the deadliest gynecological malignancy, and accounts for over 150,000
deaths per year worldwide. The high grade serous ovarian carcinoma (HGSC) subtype …

Metastasis in high-grade serous ovarian cancer (HGSOC) occurs through an
unconventional route that involves exfoliation of cancer cells from primary tumors and …

The extracellular matrix (ECM) governs a wide spectrum of cellular fate processes, with a
particular emphasis on anoikis, an integrin‐dependent form of cell death. Currently, anoikis …

Anchorage-independent growth of cancer cells in vitro is correlated to metastasis formation
in vivo. Metformin use is associated with decreased breast cancer incidence and currently …

Metastasis is the major cause of death in women with advanced ovarian cancer. Epithelial
ovarian cancer cells can dissociate directly from extracellular matrix (ECM) and form …