Engineering of global transcription factors in Bacillus, a genetic tool for increasing product yields: a bioprocess overview

SEM Tolibia, AD Pacheco, SYG Balbuena… - World Journal of …, 2023 - Springer
Transcriptional factors are well studied in bacteria for their global interactions and the effects
they produce at the phenotypic level. Particularly, Bacillus subtilis has been widely …

Bacillus anthracis Genetics and Virulence Gene Regulation

TM Koehler - Anthrax, 2002 - Springer
The Bacillus anthracis genome consists of an approximately 5.3-Mb chromosome and two
plasmids, pXO1 (182 kb) and pXO2 (96 kb). Genetic analysis has focused primarily on the …

Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli

M Inui, M Suda, S Kimura, K Yasuda, H Suzuki… - Applied microbiology …, 2008 - Springer
A recombinant butanol pathway composed of Clostridium acetobutylicum ATCC 824 genes,
thiL, hbd, crt, bcd-etfB-etfA, and adhe1 (or adhe) coding for acetyl-CoA acetyltransferase …

[图书][B] Handbook on clostridia

P Dürre - 2005 - taylorfrancis.com
Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical
and medical applications. Despite growing scientific, medical, and industrial interest …

Evolution of signalling in the sporulation phosphorelay

K Stephenson, JA Hoch - Molecular microbiology, 2002 - Wiley Online Library
Two‐component and phosphorelay signal transduction systems are believed to function as
environ‐mental sensors that programme gene expression to the composition of the …

The genetic engineering of microbial solvent production

DR Woods - Trends in Biotechnology, 1995 - cell.com
Although the production of acetone and butanol by m strains wa strains was a thriving
industrial fermentation process, it is no longer competitive with the chemical synthesis of …

Control of Anthrax Toxin Gene Expression by the Transition State Regulator abrB

E Saile, TM Koehler - Journal of Bacteriology, 2002 - Am Soc Microbiol
Bacillus anthracis produces the anthrax toxin proteins protective antigen (PA), lethal factor
(LF), and edema factor (EF) in a growth phase-dependent manner when cultured in liquid …

Efficient sporulation in Clostridium difficile requires disruption of the σK gene

JD Haraldsen, AL Sonenshein - Molecular microbiology, 2003 - Wiley Online Library
Summary A 14.6 kb prophage‐like insertion, termed skinCd, was found to interrupt the sigK
gene, which encodes an RNA polymerase sigma factor essential for sporulation, in six …

Effect of Acetate on Molecular and Physiological Aspects of Clostridium beijerinckii NCIMB 8052 Solvent Production and Strain Degeneration

CK Chen, HP Blaschek - Applied and environmental microbiology, 1999 - Am Soc Microbiol
The addition of sodium acetate to chemically defined MP2 medium was found to increase
and stabilize solvent production and also increase glucose utilization by Clostridium …

Three orphan histidine kinases inhibit Clostridioides difficile sporulation

AN Edwards, D Wetzel, MA DiCandia… - Journal of …, 2022 - Am Soc Microbiol
The ability of the anaerobic gastrointestinal pathogen Clostridioides difficile to survive
outside the host relies on the formation of dormant endospores. Spore formation is …