Engineering peroxisomal biosynthetic pathways for maximization of triterpene production in Yarrowia lipolytica
Constructing efficient cell factories for product synthesis is frequently hampered by
competing pathways and/or insufficient precursor supply. This is particularly evident in the …
competing pathways and/or insufficient precursor supply. This is particularly evident in the …
Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial β-oxidation trifunctional enzymes
SK Sah-Teli, M Pinkas, MJ Hynönen, SJ Butcher… - Structure, 2023 - cell.com
Facultative anaerobic bacteria such as Escherichia coli have two α 2 β 2 heterotetrameric
trifunctional enzymes (TFE), catalyzing the last three steps of the β-oxidation cycle: soluble …
trifunctional enzymes (TFE), catalyzing the last three steps of the β-oxidation cycle: soluble …
Insights into the stability and substrate specificity of the E. coli aerobic β-oxidation trifunctional enzyme complex
SK Sah-Teli, MJ Hynönen, R Sulu, S Dalwani… - Journal of structural …, 2020 - Elsevier
Degradation of fatty acids by the β-oxidation pathway results in the formation of acetyl-CoA
which enters the TCA cycle for the production of ATP. In E. coli, the last three steps of the β …
which enters the TCA cycle for the production of ATP. In E. coli, the last three steps of the β …
Structural enzymology studies with the substrate 3S‐hydroxybutanoyl‐CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD
S Sridhar, TR Kiema, W Schmitz, M Widersten… - FEBS Open …, 2024 - Wiley Online Library
Multifunctional enzyme, type‐1 (MFE1) catalyzes the second and third step of the β‐
oxidation cycle, being, respectively, the 2 E‐enoyl‐CoA hydratase (ECH) reaction (N …
oxidation cycle, being, respectively, the 2 E‐enoyl‐CoA hydratase (ECH) reaction (N …
Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and …
S Sridhar, W Schmitz, JK Hiltunen… - … Section D: Structural …, 2020 - journals.iucr.org
The peroxisomal multifunctional enzyme type 1 (MFE1) catalyzes two successive reactions
in the β-oxidation cycle: the 2E-enoyl-CoA hydratase (ECH) and NAD+-dependent 3S …
in the β-oxidation cycle: the 2E-enoyl-CoA hydratase (ECH) and NAD+-dependent 3S …
[PDF][PDF] Fundamental computational studies of the structural dynamical relationships of multifunctional enzyme type 1 (MFE-1)
N Herder - 2022 - depositonce.tu-berlin.de
The multifunctional enzyme type 1 (MFE-1) plays a crucial role in the fatty acid metabolism. It
is a monomeric enzyme that catalyzes three reactions in the β-oxidation pathway: the …
is a monomeric enzyme that catalyzes three reactions in the β-oxidation pathway: the …
Control of Topology and Chirality in Functional Supramolecular Systems
BH Gibber - 2022 - search.proquest.com
Knots and links are ubiquitous in both the macroscopic and biological worlds, where their
topologically distinct characteristics lend themselves to a plethora of different functions …
topologically distinct characteristics lend themselves to a plethora of different functions …
Crystallographic binding studies of rat peroxisomal multifunctional enzyme, type-1 (MFE1) with 3-ketodecanoyl-CoA: capturing active and inactive states of its …
S Sridhar, W Schmitz, JK Hiltunen, R Venkatesan… - 2020 - oulurepo.oulu.fi
The peroxisomal multifunctional enzyme type 1 (MFE1) catalyzes two successive reactions
in the β-oxidation cycle: the 2E-enoyl-CoA hydratase (ECH) and NAD⁺-dependent 3S …
in the β-oxidation cycle: the 2E-enoyl-CoA hydratase (ECH) and NAD⁺-dependent 3S …