[HTML][HTML] Application and research progress of single cell sequencing technology in leukemia

D Xie, B An, M Yang, L Wang, M Guo… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Leukemia is a malignant tumor with high heterogeneity and a complex evolutionary process.
It is difficult to resolve the heterogeneity and clonal evolution of leukemia cells by applying …

The evolutionary features and roles of single nucleotide variants and charged amino acid mutations in influenza outbreaks during NPI period

ZZ Huang, J Tan, P Huang, BS Li, Q Guo, LJ Liang - Scientific Reports, 2024 - nature.com
The epidemic and outbreaks of influenza B Victoria lineage (Bv) during 2019–2022 led to an
analysis of genetic, epitopes, charged amino acids and Bv outbreaks. Based on the National …

Phertilizer: Growing a clonal tree from ultra-low coverage single-cell DNA sequencing of tumors

LL Weber, C Zhang, I Ochoa… - PLoS computational …, 2023 - journals.plos.org
Emerging ultra-low coverage single-cell DNA sequencing (scDNA-seq) technologies have
enabled high resolution evolutionary studies of copy number aberrations (CNAs) within …

High-resolution detection of copy number alterations in single cells with HiScanner

Y Zhao, LJ Luquette, AD Veit, X Wang, R Xi… - bioRxiv, 2024 - biorxiv.org
Improvements in single-cell whole-genome sequencing (scWGS) assays have enabled
detailed characterization of somatic copy number alterations (CNAs) at the single-cell level …

DICE: Fast and Accurate Distance-Based Reconstruction of Single-Cell Copy Number Phylogenies

S Weiner, MS Bansal - bioRxiv, 2024 - biorxiv.org
Somatic copy number alterations (sCNAs) are valuable phylogenetic markers for inferring
evolutionary relationships among tumor cell subpopulations. Advances in single-cell DNA …