Wound healing: a cellular perspective

M Rodrigues, N Kosaric, CA Bonham… - Physiological …, 2019 - journals.physiology.org
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Periodontitis: a multifaceted disease of tooth-supporting tissues

E Könönen, M Gursoy, UK Gursoy - Journal of clinical medicine, 2019 - mdpi.com
Periodontitis is an infection-driven inflammatory disease in which the composition of biofilms
plays a significant role. Dental plaque accumulation at the gingival margin initiates an …

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

AJ Covarrubias, A Kale, R Perrone… - Nature …, 2020 - nature.com
Declining tissue nicotinamide adenine dinucleotide (NAD) levels are linked to ageing and its
associated diseases. However, the mechanism for this decline is unclear. Here, we show …

Efferocytosis induces macrophage proliferation to help resolve tissue injury

BD Gerlach, PB Ampomah, A Yurdagul, C Liu… - Cell metabolism, 2021 - cell.com
Apoptotic cell clearance by macrophages (efferocytosis) promotes resolution signaling
pathways, which can be triggered by molecules derived from the phagolysosomal …

[HTML][HTML] The impact of the lung environment on macrophage development, activation and function: diversity in the face of adversity

CC Bain, AS MacDonald - Mucosal immunology, 2022 - Elsevier
The last decade has been somewhat of a renaissance period for the field of macrophage
biology. This renewed interest, combined with the advent of new technologies and …

The good and the bad: Monocytes' and macrophages' diverse functions in inflammation

J Austermann, J Roth, K Barczyk-Kahlert - Cells, 2022 - mdpi.com
Monocytes and macrophages are central players of the innate immune response and play a
pivotal role in the regulation of inflammation. Thereby, they actively participate in all phases …

[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus

MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Macrophages in wound healing: activation and plasticity

SY Kim, MG Nair - Immunology and cell biology, 2019 - Wiley Online Library
Macrophages are critically involved in wound healing, from dampening inflammation to
clearing cell debris and coordinating tissue repair. Within the wound, the complexity of …

A micro/nano-biomimetic coating on titanium orchestrates osteo/angio-genesis and osteoimmunomodulation for advanced osseointegration

L Bai, P Chen, Y Zhao, R Hang, X Yao, B Tang, C Liu… - Biomaterials, 2021 - Elsevier
Osseointegration is a sophisticated bone and implant healing process comprising of initial
hematoma formation, immediate osteoimmunomodulation, angiogenesis, and osteogenesis …

Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression

JW Williams, K Zaitsev, KW Kim, S Ivanov… - Nature …, 2020 - nature.com
Early atherosclerosis depends upon responses by immune cells resident in the intimal aortic
wall. Specifically, the healthy intima is thought to be populated by vascular dendritic cells …