Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Understanding the co-epidemic of obesity and COVID-19: current evidence, comparison with previous epidemics, mechanisms, and preventive and therapeutic …

M Dalamaga, GS Christodoulatos, I Karampela… - Current obesity …, 2021 - Springer
Purpose of Review A growing body of evidence suggests that obesity and increased visceral
adiposity are strongly and independently linked to adverse outcomes and death due to …

Genomics and phenomics of body mass index reveals a complex disease network

J Huang, JE Huffman, Y Huang, Í Do Valle… - Nature …, 2022 - nature.com
Elevated body mass index (BMI) is heritable and associated with many health conditions
that impact morbidity and mortality. The study of the genetic association of BMI across a …

A proteome-scale map of the SARS-CoV-2–human contactome

DK Kim, B Weller, CW Lin, D Sheykhkarimli… - Nature …, 2023 - nature.com
Understanding the mechanisms of coronavirus disease 2019 (COVID-19) disease severity
to efficiently design therapies for emerging virus variants remains an urgent challenge of the …

Identifying factors contributing to increased susceptibility to COVID-19 risk: a systematic review of Mendelian randomization studies

S Luo, Y Liang, THT Wong… - International journal …, 2022 - academic.oup.com
Background To summarize modifiable factors for coronavirus disease 2019 (COVID-19)
suggested by Mendelian randomization studies. Methods In this systematic review, we …

Mental health and obesity during the COVID-19 pandemic

OC Melamed, P Selby, VH Taylor - Current Obesity Reports, 2022 - Springer
Abstract Purpose of Review The COVID-19 pandemic is associated with increased levels of
stress, anxiety and depression in the population. These are associated with unhealthy …

Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization

GA Pathak, K Singh, TW Miller-Fleming… - Nature …, 2021 - nature.com
Despite rapid progress in characterizing the role of host genetics in SARS-Cov-2 infection,
there is limited understanding of genes and pathways that contribute to COVID-19. Here, we …

Educational attainment decreases the risk of COVID-19 severity in the European population: a two-sample Mendelian randomization study

M Yoshikawa, K Asaba - Frontiers in public health, 2021 - frontiersin.org
Observational studies have reported that the severity of COVID-19 depends not only on
physical conditions but also on socioeconomic status, including educational level. Because …

Biomarkers associated with severe COVID-19 among populations with high cardiometabolic risk: a 2-sample mendelian randomization study

T Sood, N Perrot, M Chong… - JAMA Network …, 2023 - jamanetwork.com
Importance Cardiometabolic parameters are established risk factors for COVID-19 severity.
The identification of causal or protective biomarkers for COVID-19 severity may facilitate the …

[HTML][HTML] The bidirectional interaction of COVID-19 infections and lipoproteins

KR Feingold - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
COVID-19 infections decrease total cholesterol, LDL-C, HDL-C, and apolipoprotein AI, A-II,
and B levels while triglyceride levels may be increased or inappropriately normal for the …