The global H5N1 influenza panzootic in mammals

TP Peacock, L Moncla, G Dudas, D VanInsberghe… - Nature, 2025 - nature.com
Influenza A viruses have caused more documented global pandemics in human history than
any other pathogen,. High pathogenicity avian influenza viruses belonging to the H5N1 …

An update on highly pathogenic avian influenza A (H5N1) virus, clade 2.3. 4.4 b

RJ Webby, TM Uyeki - The Journal of Infectious Diseases, 2024 - academic.oup.com
Since the resurgence of highly pathogenic avian influenza (HPAI) A (H5N1) virus, clade 2.3.
4.4 b, during 2021, these viruses have spread widely among birds worldwide, causing …

Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance

B Dadonaite, JJ Ahn, JT Ort, J Yu, C Furey… - PLoS …, 2024 - journals.plos.org
H5 influenza is considered a potential pandemic threat. Recently, H5 viruses belonging to
clade 2.3. 4.4 b have caused large outbreaks in avian and multiple nonhuman mammalian …

Multiple transatlantic incursions of highly pathogenic avian influenza clade 2.3. 4.4 b A (H5N5) virus into North America and spillover to mammals

CNG Erdelyan, A Kandeil, AV Signore, MEB Jones… - Cell reports, 2024 - cell.com
Highly pathogenic avian influenza (HPAI) viruses have spread at an unprecedented scale,
leading to mass mortalities in birds and mammals. In 2023, a transatlantic incursion of HPAI …

Epidemiological data of an influenza A/H5N1 outbreak in elephant seals in Argentina indicates mammal-to-mammal transmission

MM Uhart, RET Vanstreels, MI Nelson, V Olivera… - Nature …, 2024 - nature.com
H5N1 high pathogenicity avian influenza virus has killed thousands of marine mammals in
South America since 2022. Here we report epidemiological data and full genome …

The mammary glands of cows abundantly display receptors for circulating avian H5 viruses

M Ríos Carrasco, A Gröne, JMA van den Brand… - Journal of …, 2024 - journals.asm.org
Influenza A viruses (IAVs) from the H5N1 2.3. 4.4 b clade are circulating in dairy farms in the
USA.; ruminants were presumed not to be hosts for IAVs. Previously, IAV-positive …

The panzootic spread of highly pathogenic avian influenza H5N1 sublineage 2.3. 4.4 b: a critical appraisal of One Health preparedness and prevention

MPG Koopmans, CB Behravesh… - The Lancet Infectious …, 2024 - thelancet.com
Changes in the epidemiology and ecology of H5N1 highly pathogenic avian influenza are
devastating wild bird and poultry populations, farms and communities, and wild mammals …

Genomic characterization of highly pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle

X Hu, A Saxena, DR Magstadt, PC Gauger… - Emerging microbes & …, 2024 - Taylor & Francis
In March 2024, the emergence of highly pathogenic avian influenza (HPAI) A (H5N1)
infections in dairy cattle was detected in the United Sates for the first time. We genetically …

Ecology and evolution of avian influenza viruses

Y Bi, J Yang, L Wang, L Ran, GF Gao - Current Biology, 2024 - cell.com
Four types of influenza virus have been identified in nature: influenza A, B, and C viruses are
capable of infecting humans, and influenzas A and B cause annual epidemics (seasonal flu) …

Avian influenza viruses in wild birds in Canada following incursions of highly pathogenic H5N1 virus from Eurasia in 2021–2022

JA Giacinti, AV Signore, MEB Jones, L Bourque, S Lair… - Mbio, 2024 - journals.asm.org
Following the detection of novel highly pathogenic avian influenza virus (HPAIV) H5N1
clade 2.3. 4.4 b in Newfoundland, Canada, in late 2021, avian influenza virus (AIV) …