Force measurements with the atomic force microscope: Technique, interpretation and applications
The atomic force microscope (AFM) is not only a tool to image the topography of solid
surfaces at high resolution. It can also be used to measure force-versus-distance curves …
surfaces at high resolution. It can also be used to measure force-versus-distance curves …
Biological and environmental interactions of emerging two-dimensional nanomaterials
Two-dimensional materials have become a major focus in materials chemistry research
worldwide with substantial efforts centered on synthesis, property characterization, and …
worldwide with substantial efforts centered on synthesis, property characterization, and …
[HTML][HTML] For whom the bubble grows: physical principles of bubble nucleation and dynamics in histotripsy ultrasound therapy
Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …
[HTML][HTML] Dividing cells regulate their lipid composition and localization
GE Atilla-Gokcumen, E Muro, J Relat-Goberna… - Cell, 2014 - cell.com
Although massive membrane rearrangements occur during cell division, little is known about
specific roles that lipids might play in this process. We report that the lipidome changes with …
specific roles that lipids might play in this process. We report that the lipidome changes with …
Interactions of platelets with circulating tumor cells contribute to cancer metastasis
S Anvari, E Osei, N Maftoon - Scientific Reports, 2021 - nature.com
Recent studies have suggested that platelets have a crucial role in enhancing the survival of
circulating tumor cells in the bloodstream and aggravating cancer metastasis. The main …
circulating tumor cells in the bloodstream and aggravating cancer metastasis. The main …
FluidFM: combining atomic force microscopy and nanofluidics in a universal liquid delivery system for single cell applications and beyond
We describe the fluidFM, an atomic force microscope (AFM) based on hollow cantilevers for
local liquid dispensing and stimulation of single living cells under physiological conditions. A …
local liquid dispensing and stimulation of single living cells under physiological conditions. A …
Nuclear rupture at sites of high curvature compromises retention of DNA repair factors
The nucleus is physically linked to the cytoskeleton, adhesions, and extracellular matrix—all
of which sustain forces, but their relationships to DNA damage are obscure. We show that …
of which sustain forces, but their relationships to DNA damage are obscure. We show that …
Membrane tension and cytoskeleton organization in cell motility
P Sens, J Plastino - Journal of Physics: Condensed Matter, 2015 - iopscience.iop.org
Cell membrane shape changes are important for many aspects of normal biological function,
such as tissue development, wound healing and cell division and motility. Various disease …
such as tissue development, wound healing and cell division and motility. Various disease …
Membrane tension in rapidly moving cells is determined by cytoskeletal forces
AD Lieber, S Yehudai-Resheff, EL Barnhart, JA Theriot… - Current biology, 2013 - cell.com
Background Membrane tension plays an essential role in cell motility. The load imposed by
the tensed membrane restrains actin polymerization, promotes rear retraction, and …
the tensed membrane restrains actin polymerization, promotes rear retraction, and …
Molecular tension probes for imaging forces at the cell surface
Conspectus Mechanical forces are essential for a variety of biological processes ranging
from transcription and translation to cell adhesion, migration, and differentiation. Through the …
from transcription and translation to cell adhesion, migration, and differentiation. Through the …