Acute graft-versus-host disease

F Malard, E Holler, BM Sandmaier, H Huang… - Nature Reviews …, 2023 - nature.com
Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

Palliative and end-of-life care for patients with hematologic malignancies

A El-Jawahri, AM Nelson, TF Gray, SJ Lee… - Journal of Clinical …, 2020 - ascopubs.org
Hematologic malignancies are a heterogeneous group of diseases with unique illness
trajectories, treatment paradigms, and potential for curability, which affect patients' palliative …

Effect of inpatient palliative care on quality of life 2 weeks after hematopoietic stem cell transplantation: a randomized clinical trial

A El-Jawahri, T LeBlanc, H VanDusen, L Traeger… - Jama, 2016 - jamanetwork.com
Importance During hospitalization for hematopoietic stem cell transplantation (HCT), patients
receive high-dose chemotherapy before transplantation and experience significant physical …

Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease

K Matsuoka, J Koreth, HT Kim, G Bascug… - Science translational …, 2013 - science.org
CD4+ Foxp3+ regulatory T cells (Tregs) play a central role in the maintenance of immune
tolerance after allogeneic hematopoietic stem cell transplantation. We recently reported that …

Effect of inpatient palliative care during hematopoietic stem-cell transplant on psychological distress 6 months after transplant: results of a randomized clinical trial

A El-Jawahri, L Traeger, JA Greer… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Inpatient palliative care integrated with transplant care improves patients' quality of
life (QOL) and symptom burden during hematopoietic stem-cell transplant (HCT). We …

[HTML][HTML] Long-term complications after hematopoietic cell transplantation

NS Majhail - Hematology/oncology and stem cell therapy, 2017 - Elsevier
The prevalence of autologous and allogeneic hematopoietic cell transplantation (HCT)
survivors continues to increase. Among patients whose disease remains in remission for the …

Patient-reported quality of life is associated with severity of chronic graft-versus-host disease as measured by NIH criteria: report on baseline data from the Chronic …

J Pidala, B Kurland, X Chai, N Majhail… - Blood, The Journal …, 2011 - ashpublications.org
Quality of life (QOL) after hematopoietic cell transplantation (HCT) is compromised by
chronic GVHD. In a prospectively assembled multicenter cohort of adults with chronic GVHD …

Managing high-risk CLL during transition to a new treatment era: stem cell transplantation or novel agents?

P Dreger, J Schetelig, N Andersen… - Blood, The Journal …, 2014 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (HSCT) has been considered as the
treatment of choice for patients with high-risk chronic lymphocytic leukemia (HR-CLL; ie …

Quality of life and mood of patients and family caregivers during hospitalization for hematopoietic stem cell transplantation

AR El‐Jawahri, LN Traeger, K Kuzmuk, JR Eusebio… - Cancer, 2015 - Wiley Online Library
BACKGROUND We conducted a study to investigate the impact of hospitalization for
hematopoietic stem cell transplantation (HCT) on the quality of life (QOL) and mood of …

PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy

T Asano, Y Meguri, T Yoshioka, Y Kishi… - Blood, The Journal …, 2017 - ashpublications.org
Abstract CD4+ Foxp3+ regulatory T cells (Tregs) play a central role in the maintenance of
immune tolerance after hematopoietic stem cell transplantation. We previously reported that …