Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects

H Abdelkafi, B Nay - Natural product reports, 2012 - pubs.rsc.org
Covering: up to 2012 The Cephalotaxus genus belongs to the Cephalotaxaceae family of
conifers. Over the past decades it has proved to be a fruitful source of interesting natural …

Synthesis of naturally occurring tropones and tropolones

N Liu, W Song, CM Schienebeck, M Zhang, W Tang - Tetrahedron, 2014 - Elsevier
Tropones and tropolones refer to non-benzenoid seven-membered aromatic compounds
with a carbonyl group (Scheme 1), which are also called troponoids or tropolonoids …

Asymmetric total syntheses of cephalotane-type diterpenoids cephanolides A–D

Z Qing, P Mao, T Wang, H Zhai - Journal of the American …, 2022 - ACS Publications
Cephanolides A–D are cephalotane-type diterpenoids featuring a novel 6/6/6/5 tetracyclic
core embedded with a bridged δ-lactone. The asymmetric and divergent total syntheses of …

Stereoselective total synthesis of hainanolidol and harringtonolide via oxidopyrylium-based [5+ 2] cycloaddition

M Zhang, N Liu, W Tang - Journal of the American Chemical …, 2013 - ACS Publications
The tetracyclic carbon skeleton of hainanolidol and harringtonolide was efficiently
constructed by an intramolecular oxidopyrylium-based [5+ 2] cycloaddition. An anionic ring …

Total Synthesis of (±)-Cephanolides B and C via a Palladium-Catalyzed Cascade Cyclization and Late-Stage sp3 C–H Bond Oxidation

L Xu, C Wang, Z Gao, YM Zhao - Journal of the American …, 2018 - ACS Publications
Herein, we report the first total syntheses of complex cephalotaxus diterpenoids cephanolide
B and C from commercially available 5-bromo-2-methylanisole. Key to the success of this …

Progress in structure, synthesis and biological activity of natural cephalotane diterpenoids

C Jiang, J Xue, Y Yuan, Y Li, C Zhao, Q Jing, X Zhang… - Phytochemistry, 2021 - Elsevier
The Cephalotaxus genus is well-known owing to the numerous complex, biologically
relevant natural products that can be obtained from its constituent species. The successful …

Asymmetric total synthesis of (+)‐Mannolide C

Q Ao, HJ Zhang, J Zheng, X Chen… - Angewandte Chemie …, 2021 - Wiley Online Library
Mannolide C is a complex hexacyclic C20 cephalotane‐type diterpenoid featuring a highly
strained 7/6/6/5 tetracyclic core containing eight consecutive stereocenters and two bridging …

Cephanolides A–J, Cephalotane-Type Diterpenoids from Cephalotaxus sinensis

YY Fan, JB Xu, HC Liu, LS Gan, J Ding… - Journal of natural …, 2017 - ACS Publications
Ten new cephalotane-type diterpenoids, cephanolides A–J (1–10), and two known
analogues were isolated and characterized from Cephalotaxus sinensis. Compounds 1–3 …

Total synthesis of (+)‐3‐Deoxyfortalpinoid F,(+)‐Fortalpinoid A, and (+)‐Cephinoid H

Z Ren, Z Sun, Y Li, X Fan, M Dai… - Angewandte Chemie …, 2021 - Wiley Online Library
Deoxyfortalpinoid F, fortalpinoid A, and cephinoid H are members of the Cephalotaxus
diterpenoids class of natural products, which feature diverse chemical structures and …

Stereodivergence in amine-catalyzed regioselective [4+ 2] cycloadditions of β-substituted cyclic enones and polyconjugated malononitriles

X Feng, Z Zhou, R Zhou, QQ Zhou… - Journal of the …, 2012 - ACS Publications
Switchable reaction patterns of β-substituted cyclic enones via amine-based dienamine
activation are reported. While γ-regioselective vinylogous Michael addition was observed …