Quantitating the subtleties of microglial morphology with fractal analysis

A Karperien, H Ahammer, HF Jelinek - Frontiers in cellular …, 2013 - frontiersin.org
It is well established that microglial form and function are inextricably linked. In recent years,
the traditional view that microglial form ranges between “ramified resting” and “activated …

Microglia morphological categorization in a rat model of neuroinflammation by hierarchical cluster and principal components analysis

MM Fernández-Arjona, JM Grondona… - Frontiers in cellular …, 2017 - frontiersin.org
It is known that microglia morphology and function are closely related, but only few studies
have objectively described different morphological subtypes. To address this issue …

Fractals in the nervous system: conceptual implications for theoretical neuroscience

G Werner - Frontiers in physiology, 2010 - frontiersin.org
This essay is presented with two principal objectives in mind: first, to document the
prevalence of fractals at all levels of the nervous system, giving credence to the notion of …

A Review of Theoretical Perspectives in Cognitive Science on the Presence of 1/f Scaling in Coordinated Physiological and Cognitive Processes

ML Wijnants - Journal of Nonlinear Dynamics, 2014 - Wiley Online Library
Time series of human performances present fluctuations around a mean value. These
fluctuations are typically considered as insignificant, and attributable to random noise. Over …

The kynurenic acid analog SZR104 induces cytomorphological changes associated with the anti-inflammatory phenotype in cultured microglia

M Szabo, N Lajkó, K Dulka, G Barczánfalvi… - Scientific Reports, 2023 - nature.com
We previously showed the anti-inflammatory effects of kynurenic acid (KYNA) and its brain-
penetrable analog N-(2-(dimethylamino) ethyl)-3-(morpholinomethyl)-4-hydroxyquinoline-2 …

Convergent evolution of an extreme dietary specialisation, the olfactory system of worm-eating rodents

Q Martinez, R Lebrun, AS Achmadi, JA Esselstyn… - Scientific reports, 2018 - nature.com
Turbinal bones are key components of the mammalian rostrum that contribute to three
critical functions:(1) homeothermy,(2) water conservation and (3) olfaction. With over 700 …

Fractal, multifractal, and lacunarity analysis of microglia in tissue engineering

AL Karperien, HF Jelinek - Frontiers in bioengineering and …, 2015 - frontiersin.org
Tissue engineering is currently one of the most exciting fields in biology (Grayson et al.,
2009). Fractal analysis is equally exciting (Di Ieva et al., 2013), as is the study of microglia …

The Temporal Relationship between Blood–Brain Barrier Integrity and Microglial Response following Neonatal Hypoxia Ischemia

A Jithoo, TR Penny, Y Pham, AE Sutherland, MJ Smith… - Cells, 2024 - mdpi.com
Blood–brain barrier (BBB) dysfunction and neuroinflammation are key mechanisms of brain
injury. We performed a time-course study following neonatal hypoxia–ischemia (HI) to …

Practical quantitative lithic use-wear analysis using multiple classifiers

NE Stevens, DR Harro, A Hicklin - Journal of Archaeological Science, 2010 - Elsevier
Although use-wear analysis of prehistoric stone tools using conventional microscopy has
proven useful to archaeologists interested in tool function, critics have questioned the …

Sex-specific microglial responses to glucocerebrosidase inhibition: relevance to GBA1-linked Parkinson's disease

E Brunialti, A Villa, M Toffoli, S Lucas Del Pozo, N Rizzi… - Cells, 2023 - mdpi.com
Microglia are heterogenous cells characterized by distinct populations each contributing to
specific biological processes in the nervous system, including neuroprotection. To elucidate …