Antimicrobial peptides: features, applications and the potential use against covid-19

DM Mabrouk - Molecular Biology Reports, 2022 - Springer
Abstract Background Antimicrobial peptides (AMPs) are a diverse class of molecules that
represent a vital part of innate immunity. AMPs are evolutionarily conserved molecules that …

Common methods in mitochondrial research

Y Yin, H Shen - International Journal of Molecular …, 2022 - spandidos-publications.com
Mitochondrial abnormalities are primarily seen in morphology, structure and function. They
can cause damage to organs, including the heart, brain and muscle, by various …

Antitumor effects of scorpion peptide Smp43 through mitochondrial dysfunction and membrane disruption on hepatocellular carcinoma

J Chai, W Yang, Y Gao, R Guo, Q Peng… - Journal of natural …, 2021 - ACS Publications
Smp43, a cationic antimicrobial peptide identified from the venom gland of the Egyptian
scorpion Scorpio maurus palmatus, shows cytotoxicity toward hepatoma cell line HepG2 by …

Small molecule interferences in resazurin and MTT-based metabolic assays in the absence of cells

BH Neufeld, JB Tapia, A Lutzke… - Analytical …, 2018 - ACS Publications
In vitro assays (such as resazurin and MTT) provide an opportunity to determine the
cytotoxicity of novel therapeutics before moving forward with expensive and resource …

The cationic cell‐penetrating KT2 peptide promotes cell membrane defects and apoptosis with autophagy inhibition in human HCT 116 colon cancer cells

P Maraming, S Klaynongsruang… - Journal of Cellular …, 2019 - Wiley Online Library
The anticancer activity of cationic antimicrobial peptides (AMPs) has become more
interesting because some AMPs have selective recognition against cancer cells. However …

J591 functionalized paclitaxel-loaded PLGA nanoparticles successfully inhibited PSMA overexpressing LNCaP cells

I Ehsan, L Kumari, R Sen, A Al Hoque… - Journal of Drug Delivery …, 2022 - Elsevier
To evaluate the chemotherapeutic efficacy of J591 fabricated poly (d, l)-lactic-co-glycolic
acid (PLGA) nanoparticles containing paclitaxel (Ab-PTX-NP) in vitro in PSMA (prostate …

Role of intracranial bone marrow mesenchymal stem cells in stroke recovery: A focus on post-stroke inflammation and mitochondrial transfer

J Ming, Y Liao, W Song, Z Wang, J Cui, L He, G Chen… - Brain Research, 2024 - Elsevier
Stem cell therapy has become a hot research topic in the medical field in recent years, with
enormous potential for treating a variety of diseases. In particular, bone marrow …

A novel epididymal quiescence factor inhibits sperm motility by modulating NOS activity and intracellular NO‐cGMP pathway

P Ghosh, S Mukherjee, A Bhoumik… - Journal of Cellular …, 2018 - Wiley Online Library
Mature and potentially motile spermatozoa stored in cauda epididymis in an inactive state
for approximately 30 days; however, during ejaculation they regain motility. To understand …

[HTML][HTML] A review emphasizing on utility of heptad repeat sequence as a tool to design pharmacologically safe peptide-based antibiotics

V Yadav, R Misra - Biochimie, 2021 - Elsevier
Extensive usage of antibiotics has created an unprecedented scenario of the rapid
emergence of many drug-resistant bacteria, which has become an alarming public health …

A CCR5 antagonist-based HIV entry inhibitor exhibited potent spermicidal activity: Potential application for contraception and prevention of HIV sexual transmission

M Yang, R Zhi, L Lu, M Dong, Y Wang, F Tian… - European Journal of …, 2018 - Elsevier
B07 is a small-molecule CCR5 antagonist-based HIV-1 entry inhibitor that is being
developed as an anti-HIV microbicide for preventing sexual transmission of HIV. Here we …