Gastric adenocarcinoma: review and considerations for future directions
Objective: This update reviews the epidemiology and surgical management, and the
controversies of gastric adenocarcinoma. We provide the relevance of outcome data to …
controversies of gastric adenocarcinoma. We provide the relevance of outcome data to …
Machine learning for lung cancer diagnosis, treatment, and prognosis
The recent development of imaging and sequencing technologies enables systematic
advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in …
advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in …
Repeated observation of breast tumor subtypes in independent gene expression data sets
Characteristic patterns of gene expression measured by DNA microarrays have been used
to classify tumors into clinically relevant subgroups. In this study, we have refined the …
to classify tumors into clinically relevant subgroups. In this study, we have refined the …
Classification of human cancer diseases by gene expression profiles
A cancers disease in virtually any of its types presents a significant reason behind death
surrounding the world. In cancer analysis, classification of varied tumor types is of the …
surrounding the world. In cancer analysis, classification of varied tumor types is of the …
Serum MicroRNA signatures identified in a genome-wide serum MicroRNA expression profiling predict survival of non–small-cell lung cancer
Z Hu, X Chen, Y Zhao, T Tian, G Jin, Y Shu… - Journal of clinical …, 2010 - ascopubs.org
Purpose Recent findings that human serum contains stably expressed microRNA (miRNA)
have revealed a great potential of serum miRNA signature as disease fingerprints to predict …
have revealed a great potential of serum miRNA signature as disease fingerprints to predict …
Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study
Nature medicine, 2008 - nature.com
Although prognostic gene expression signatures for survival in early-stage lung cancer have
been proposed, for clinical application, it is critical to establish their performance across …
been proposed, for clinical application, it is critical to establish their performance across …
[HTML][HTML] A five-gene signature and clinical outcome in non–small-cell lung cancer
Background Current staging methods are inadequate for predicting the outcome of treatment
of non–small-cell lung cancer (NSCLC). We developed a five-gene signature that is closely …
of non–small-cell lung cancer (NSCLC). We developed a five-gene signature that is closely …
Prognostic and predictive gene signature for adjuvant chemotherapy in resected non–small-cell lung cancer
CQ Zhu, K Ding, D Strumpf, BA Weir… - Journal of clinical …, 2010 - ascopubs.org
Purpose The JBR. 10 trial demonstrated benefit from adjuvant cisplatin/vinorelbine (ACT) in
early-stage non–small-cell lung cancer (NSCLC). We hypothesized that expression profiling …
early-stage non–small-cell lung cancer (NSCLC). We hypothesized that expression profiling …
Biomarker discovery in non–small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation
J Botling, K Edlund, M Lohr, B Hellwig, L Holmberg… - Clinical cancer …, 2013 - AACR
Purpose: Global gene expression profiling has been widely used in lung cancer research to
identify clinically relevant molecular subtypes as well as to predict prognosis and therapy …
identify clinically relevant molecular subtypes as well as to predict prognosis and therapy …
A 12-gene set predicts survival benefits from adjuvant chemotherapy in non–small cell lung cancer patients
Purpose: Prospectively identifying who will benefit from adjuvant chemotherapy (ACT) would
improve clinical decisions for non–small cell lung cancer (NSCLC) patients. In this study, we …
improve clinical decisions for non–small cell lung cancer (NSCLC) patients. In this study, we …