Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

The most widely used medications in dentistry are local anesthetics (LA), especially
lidocaine, and the number of recorded adverse allergic responses, particularly of hazardous …

Perioperative immediate hypersensitivity reactions are rare. Subsequent allergy
investigation is complicated by multiple simultaneous drug exposures, the use of drugs with …

Coronary angiography and heart catheterization are invaluable tests for the detection and
quantification of coronary artery disease, identification of valvular and other structural …

Suspected perioperative allergic reactions are rare but can be life-threatening. The
diagnosis is difficult to make in the perioperative setting, but prompt recognition and correct …

Local anesthetics have been used clinically for more than a century, but new insights into
their mechanisms of action and their interaction with biological systems continue to surprise …

Kounis syndrome is the concurrence of acute coronary syndromes with conditions
associated with mast cell activation, such as allergies or hypersensitivity and anaphylactic or …

This review seeks to address 10 essential questions regarding the clinical use of local
anaesthetics. Each local anaesthetic has distinctive physicochemical properties but with the …

Perioperative anaphylaxis is a severe adverse event during anesthesia that requires prompt
diagnosis and treatment by physicians, including anesthesiologists. Muscle relaxants and …

Perioperative anaphylaxis is a life-threatening clinical condition that is typically the result of
drugs or substances used for anesthesia or surgery. The most common cause of …