Financing biomedical innovation

AW Lo, RT Thakor - Annual Review of Financial Economics, 2022 - annualreviews.org
We review the recent literature on financing biomedical innovation, with a specific focus on
the drug development process and how it may be enhanced to improve outcomes. We begin …

COVID-19: molecular targets, drug repurposing and new avenues for drug discovery

MR Senger, TCS Evangelista, RF Dantas… - Memórias do Instituto …, 2020 - SciELO Brasil
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare …

Information disclosure and competitive dynamics: Evidence from the pharmaceutical industry

J Kao - Management Science, 2024 - pubsonline.informs.org
This paper studies how competitive dynamics shape innovative firms' voluntary disclosure of
product quality information. Our empirical context is the pharmaceutical industry, where firms …

High risk, low return (and vice versa): the effect of product innovation on firm performance in a transition economy

X Li, F Vermeulen - Academy of Management Journal, 2021 - journals.aom.org
Common wisdom suggests that high-risk strategies will be associated with high expected
returns and vice versa. Focusing on the effect of new product development on firm …

Mapping Markush

S Wagner, C Sternitzke, S Walter - Research Policy, 2022 - Elsevier
Markush structures are molecular skeletons containing not only specific atoms but also
placeholders to represent broad sets of chemical (sub) structures. As genus claims, they …

Procurement institutions and essential drug supply in low and middle-income countries

LX Wang, NB Zahur - Available at SSRN 3926761, 2024 - papers.ssrn.com
International procurement institutions have played an important role in drug supply. This
paper studies price, delivery, and procurement lead time of drug supply for major infectious …

The alignment of innovation policy and social welfare: evidence from pharmaceuticals

MK Kyle - Innovation Policy and the Economy, 2020 - journals.uchicago.edu
This chapter provides an overview of different innovation policies and their performance in
the pharmaceutical sector. I emphasize three points. First, both push and pull policies have …

Patent term extensions and commercialization lags in the pharmaceutical industry: A growth-theoretic analysis

MY Hu, YX Lu, C Lai - Journal of Macroeconomics, 2023 - Elsevier
Due to the lags in commercialization, the effective life of a patent is generally less than its
statutory term. We introduce commercialization lags into the Schumpeterian growth model …

One product, many patents: Imperfect intellectual property rights in the pharmaceutical industry

C Gupta - Many Patents: Imperfect Intellectual Property Rights in …, 2023 - papers.ssrn.com
Economists' standard notion of intellectual property rights considers a single patent per
product, with a clearly defined scope, certain enforcement, and a fixed term of monopoly …

[HTML][HTML] Global drug diffusion and innovation with the medicines patent pool

LX Wang - Journal of Health Economics, 2022 - Elsevier
This paper studies the impact of the first joint licensing platform for patented drugs, the
Medicines Patent Pool, on global drug diffusion and innovation. The pool allows generic …