Experimental models to study epithelial-mesenchymal transition in proliferative vitreoretinopathy
A Datlibagi, A Zein-El-Din, M Frohly… - International journal of …, 2023 - mdpi.com
Proliferative vitreoretinal diseases (PVDs) encompass proliferative vitreoretinopathy (PVR),
epiretinal membranes, and proliferative diabetic retinopathy. These vision-threatening …
epiretinal membranes, and proliferative diabetic retinopathy. These vision-threatening …
Targeting the endocannabinoid system: a predictive, preventive, and personalized medicine-directed approach to the management of brain pathologies
Cannabis-inspired medical products are garnering increasing attention from the scientific
community, general public, and health policy makers. A plethora of scientific literature …
community, general public, and health policy makers. A plethora of scientific literature …
Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference
QR Liu, A Canseco-Alba, HY Zhang, P Tagliaferro… - Scientific reports, 2017 - nature.com
Abstract Cannabinoid CB2 receptors (CB2Rs) are expressed in mouse brain dopamine (DA)
neurons and are involved in several DA-related disorders. However, the cell type-specific …
neurons and are involved in several DA-related disorders. However, the cell type-specific …
The Cannabinoids Δ8THC, CBD, and HU-308 Act via Distinct Receptors to Reduce Corneal Pain and Inflammation
Abstract Background and Purpose: Corneal injury can result in dysfunction of corneal
nociceptive signaling and corneal sensitization. Activation of the endocannabinoid system …
nociceptive signaling and corneal sensitization. Activation of the endocannabinoid system …
[HTML][HTML] Keratoendotheliitis fugax hereditaria
Keratoendotheliitis Fugax Hereditaria - Abstract - Europe PMC Sign in | Create an account
https://orcid.org Europe PMC Menu About Tools Developers Help Contact us Helpdesk Feedback …
https://orcid.org Europe PMC Menu About Tools Developers Help Contact us Helpdesk Feedback …
[HTML][HTML] Comprehensive Assessment of Cannabidiol and HU308 in Acute and Chronic Colitis Models: Efficacy, Safety, and Mechanistic Innovations
Cannabinoids are emerging as promising treatments for inflammatory diseases such as
ulcerative colitis. Specifically, cannabinoid 2 (CB2) receptors, which are upregulated during …
ulcerative colitis. Specifically, cannabinoid 2 (CB2) receptors, which are upregulated during …
Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy
M Liao, X Zhu, Y Lu, X Yi, Y Hu, Y Zhao, Z Ye… - Nature …, 2024 - nature.com
During the progression of proliferative vitreoretinopathy (PVR) following ocular trauma,
previously quiescent retinal pigment epithelial (RPE) cells transition into a state of rapid …
previously quiescent retinal pigment epithelial (RPE) cells transition into a state of rapid …
Selective cannabinoid 2 receptor agonists as potential therapeutic drugs for the treatment of endotoxin-induced uveitis
RF Porter, AM Szczesniak, JT Toguri, S Gebremeskel… - Molecules, 2019 - mdpi.com
(1) Background: The cannabinoid 2 receptor (CB2R) is a promising anti-inflammatory drug
target and development of selective CB2R ligands may be useful for treating sight …
target and development of selective CB2R ligands may be useful for treating sight …
Antibacterial and analgesic properties of beta-caryophyllene in a murine urinary tract infection model
Beta-caryophyllene has demonstrated anti-inflammatory effects in a variety of conditions,
including interstitial cystitis. These effects are mediated primarily via the activation of the …
including interstitial cystitis. These effects are mediated primarily via the activation of the …
Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and …
S Papadogkonaki, D Spyridakos… - International Journal of …, 2023 - mdpi.com
The endocannabinoid system (ECS) is a new target for the development of retinal disease
therapeutics, whose pathophysiology involves neurodegeneration and neuroinflammation …
therapeutics, whose pathophysiology involves neurodegeneration and neuroinflammation …