Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

High‐aspect‐ratio nanostructured surfaces as biological metamaterials

SG Higgins, M Becce… - Advanced …, 2020 - Wiley Online Library
Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Single particle automated Raman trapping analysis of breast cancer cell-derived extracellular vesicles as cancer biomarkers

J Penders, A Nagelkerke, EM Cunnane, SV Pedersen… - ACS …, 2021 - ACS Publications
Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …

Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis

J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …

SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping

JA Huang, MZ Mousavi, Y Zhao, A Hubarevich… - Nature …, 2019 - nature.com
Surface-enhanced Raman spectroscopy (SERS) sensing of DNA bases by plasmonic
nanopores could pave a way to novel methods for DNA analyses and new generation single …

A hair fiber inspired bio-based adhesive with high bonding strength and mildew tolerance

G Zeng, Y Zhou, Y Liang, F Zhang, J Luo, J Li… - Chemical Engineering …, 2022 - Elsevier
Soybean protein (SP)-based adhesives present low adhesive strength, poor water
resistance and low mildew resistance, which generally limit their practical industrial …

Scalable trapping of single nanosized extracellular vesicles using plasmonics

C Hong, JC Ndukaife - Nature Communications, 2023 - nature.com
Heterogeneous nanoscale extracellular vesicles (EVs) are of significant interest for disease
detection, monitoring, and therapeutics. However, trapping these nano-sized EVs using …

A perspective on bleb and empty LNP structures

JB Simonsen - Journal of Controlled Release, 2024 - Elsevier
Although lipid nanoparticles (LNPs) have been FDA-approved for mRNA delivery, there is
still much to learn about these fascinating multi-component delivery systems. Here, I discuss …

Recent advances in single extracellular vesicle detection methods

SU Wang, A Khan, R Huang, S Ye, K Di… - Biosensors and …, 2020 - Elsevier
Extracellular vesicles (EVs) are secreted by a variety of cells. They are known for their
pertinent role in intercellular communication, and participation in different pathological …